Incremental step test in patients with pulmonary hypertension.
Respir Physiol Neurobiol
; 271: 103307, 2020 01.
Article
in En
| MEDLINE
| ID: mdl-31557537
ABSTRACT
Cardiopulmonary exercise testing (CPET) on a treadmill or cycle ergometer provides an integrated assessment of the cardiorespiratory system during exertion and is widely used in clinical practice. An incremental step test (IST) can be an alternative for eliciting maximal exercise responses. Therefore, 20 patients with pre-capillary PH (65% female, 41⯱â¯15 yrs) randomly performed a symptom-limited CPET on a cycle ergometer and IST. Metabolic, cardiovascular, ventilatory and gas exchange variables were recorded during both tests. There was a greater desaturation and higher VÌO2PEAK in IST compared to CPET. The VÌO2GET, HR PEAK (% pred), ΔVÌE/ΔVÌCO2 and ΔHR/ΔVÌO2 were similar in both IST and CPET. By linear regression analyses, the work performed on IST [W = (mass × 9,8â¯m/s2 x vertical distance)] was a predictor of peak VÌO2 independent of the gender and age (r2â¯=â¯077, pâ¯=â¯0001). In conclusion, IST elicited higher peak cardiopulmonary responses and has a good agreement with known severity markers in patients with pre-capillary PH.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Oxygen Consumption
/
Walking
/
Exercise Test
/
Hypertension, Pulmonary
Type of study:
Clinical_trials
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Respir Physiol Neurobiol
Year:
2020
Document type:
Article
Affiliation country:
Brasil