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An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer.
Burr, Marian L; Sparbier, Christina E; Chan, Kah Lok; Chan, Yih-Chih; Kersbergen, Ariena; Lam, Enid Y N; Azidis-Yates, Elizabeth; Vassiliadis, Dane; Bell, Charles C; Gilan, Omer; Jackson, Susan; Tan, Lavinia; Wong, Stephen Q; Hollizeck, Sebastian; Michalak, Ewa M; Siddle, Hannah V; McCabe, Michael T; Prinjha, Rab K; Guerra, Glen R; Solomon, Benjamin J; Sandhu, Shahneen; Dawson, Sarah-Jane; Beavis, Paul A; Tothill, Richard W; Cullinane, Carleen; Lehner, Paul J; Sutherland, Kate D; Dawson, Mark A.
Affiliation
  • Burr ML; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia; Cambridge Institute for Medical Research, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK. Electronic
  • Sparbier CE; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Chan KL; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Chan YC; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia.
  • Kersbergen A; ACRF Cancer Biology and Stem Cell Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.
  • Lam EYN; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Azidis-Yates E; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia.
  • Vassiliadis D; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Bell CC; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Gilan O; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Jackson S; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia.
  • Tan L; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Wong SQ; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Hollizeck S; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Michalak EM; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Siddle HV; Department of Biological Sciences, University of Southampton, Southampton, UK; Institute for Life Sciences, University of Southampton, Southampton, UK.
  • McCabe MT; Epigenetics Research Unit, Oncology R&D, GlaxoSmithKline, Collegeville, PA, USA.
  • Prinjha RK; Epigenetics Research Unit, Oncology R&D, GlaxoSmithKline, Collegeville, PA, USA; Epigenetics Research Unit, GlaxoSmithKline, Stevenage, UK.
  • Guerra GR; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Solomon BJ; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Sandhu S; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Dawson SJ; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia; Centre for Cancer Research, University of Melbourne, Parkville, Australia.
  • Beavis PA; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Tothill RW; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia; Centre for Cancer Research, University of Melbourne, Parkville, Australia; Department of Clinical Pathology, University of Melbourne, Melbourne, VIC, Australia.
  • Cullinane C; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia.
  • Lehner PJ; Cambridge Institute for Medical Research, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.
  • Sutherland KD; ACRF Cancer Biology and Stem Cell Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3010, Australia.
  • Dawson MA; Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3052, Australia; Centre for Cancer Research, University of Melbourne, Parkville, Australia. Electronic address: mark.dawson@petermac.
Cancer Cell ; 36(4): 385-401.e8, 2019 10 14.
Article in En | MEDLINE | ID: mdl-31564637
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histocompatibility Antigens Class I / Antineoplastic Combined Chemotherapy Protocols / Gene Expression Regulation, Neoplastic / Tumor Escape / Polycomb Repressive Complex 2 / Neoplasms Limits: Animals / Female / Humans / Middle aged Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2019 Document type: Article Country of publication: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histocompatibility Antigens Class I / Antineoplastic Combined Chemotherapy Protocols / Gene Expression Regulation, Neoplastic / Tumor Escape / Polycomb Repressive Complex 2 / Neoplasms Limits: Animals / Female / Humans / Middle aged Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2019 Document type: Article Country of publication: Estados Unidos