Your browser doesn't support javascript.
loading
Rapid thymectomy of NSG mice to analyze the role of native and grafted thymi in humanized mice.
Khosravi-Maharlooei, Mohsen; Hoelzl, Markus; Li, Hao Wei; Madley, Rachel C; Waffarn, Elizabeth E; Danzl, Nichole M; Sykes, Megan.
Affiliation
  • Khosravi-Maharlooei M; Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.
  • Hoelzl M; Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.
  • Li HW; Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.
  • Madley RC; Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.
  • Waffarn EE; Department of Microbiology & Immunology, Columbia University Medical Center, Columbia University, New York, NY, USA.
  • Danzl NM; Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.
  • Sykes M; Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.
Eur J Immunol ; 50(1): 138-141, 2020 01.
Article in En | MEDLINE | ID: mdl-31583677
ABSTRACT
We developed a rapid method to remove the native mouse thymus from NSG mice, which allowed us to compare the behavior of human immune cells in the presence or absence of human T cells in human immune system mice. Removing the native mouse thymus is critical for studies of human thymopiesis in grafted thymic tissue in humanized mice.
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thymectomy / Thymus Gland / Transplantation, Heterologous Limits: Animals / Humans Language: En Journal: Eur J Immunol Year: 2020 Document type: Article Affiliation country: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thymectomy / Thymus Gland / Transplantation, Heterologous Limits: Animals / Humans Language: En Journal: Eur J Immunol Year: 2020 Document type: Article Affiliation country: Estados Unidos