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Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand.
Proto, William R; Siegel, Sasha V; Dankwa, Selasi; Liu, Weimin; Kemp, Alison; Marsden, Sarah; Zenonos, Zenon A; Unwin, Steve; Sharp, Paul M; Wright, Gavin J; Hahn, Beatrice H; Duraisingh, Manoj T; Rayner, Julian C.
Affiliation
  • Proto WR; Malaria Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, CB10 1SA, UK.
  • Siegel SV; Malaria Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, CB10 1SA, UK.
  • Dankwa S; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Liu W; Departments of Medicine and Microbiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Kemp A; Department of Microbiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Marsden S; Malaria Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, CB10 1SA, UK.
  • Zenonos ZA; Malaria Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, CB10 1SA, UK.
  • Unwin S; Malaria Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, CB10 1SA, UK.
  • Sharp PM; Chester Zoo, Chester, CH2 1LH, UK.
  • Wright GJ; School of Biosciences, University of Birmingham, Edgbaston, B15 2TT, UK.
  • Hahn BH; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.
  • Duraisingh MT; Malaria Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, CB10 1SA, UK.
  • Rayner JC; Departments of Medicine and Microbiology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Nat Commun ; 10(1): 4512, 2019 10 04.
Article in En | MEDLINE | ID: mdl-31586047
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium falciparum / Protozoan Proteins / Malaria, Falciparum / Erythrocytes / Host Specificity Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium falciparum / Protozoan Proteins / Malaria, Falciparum / Erythrocytes / Host Specificity Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido