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Evolved Aliphatic Halogenases Enable Regiocomplementary C-H Functionalization of a Pharmaceutically Relevant Compound.
Hayashi, Takahiro; Ligibel, Mathieu; Sager, Emine; Voss, Moritz; Hunziker, Jürg; Schroer, Kirsten; Snajdrova, Radka; Buller, Rebecca.
Affiliation
  • Hayashi T; Competence Center for Biocatalysis, Institute of Chemistry and Biotechnology, Zürich University of Applied Sciences, Einsiedlerstrasse 31, 8820, Wädenswil, Switzerland.
  • Ligibel M; Novartis Institutes for BioMedical Research, Global Discovery Chemistry, 4056, Basel, Switzerland.
  • Sager E; Novartis Institutes for BioMedical Research, Global Discovery Chemistry, 4056, Basel, Switzerland.
  • Voss M; Competence Center for Biocatalysis, Institute of Chemistry and Biotechnology, Zürich University of Applied Sciences, Einsiedlerstrasse 31, 8820, Wädenswil, Switzerland.
  • Hunziker J; Novartis Institutes for BioMedical Research, Global Discovery Chemistry, 4056, Basel, Switzerland.
  • Schroer K; Novartis Institutes for BioMedical Research, Global Discovery Chemistry, 4056, Basel, Switzerland.
  • Snajdrova R; Novartis Institutes for BioMedical Research, Global Discovery Chemistry, 4056, Basel, Switzerland.
  • Buller R; Competence Center for Biocatalysis, Institute of Chemistry and Biotechnology, Zürich University of Applied Sciences, Einsiedlerstrasse 31, 8820, Wädenswil, Switzerland.
Angew Chem Int Ed Engl ; 58(51): 18535-18539, 2019 12 16.
Article in En | MEDLINE | ID: mdl-31589798
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Halogenation Limits: Humans Language: En Journal: Angew Chem Int Ed Engl Year: 2019 Document type: Article Affiliation country: Suiza
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Halogenation Limits: Humans Language: En Journal: Angew Chem Int Ed Engl Year: 2019 Document type: Article Affiliation country: Suiza