Type I interferon-dependent CCL4 is induced by a cGAS/STING pathway that bypasses viral inhibition and protects infected tissue, independent of viral burden.

Parekh, Nikhil J; Krouse, Tracy E; Reider, Irene E; Hobbs, Ryan P; Ward, Brian M; Norbury, Christopher C

Parekh, Nikhil J; Krouse, Tracy E; Reider, Irene E; Hobbs, Ryan P; Ward, Brian M; Norbury, Christopher C.

Affiliation

Parekh NJ; Department of Microbiology and Immunology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America.
Krouse TE; Department of Microbiology and Immunology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America.
Reider IE; Department of Microbiology and Immunology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America.
Hobbs RP; Department of Microbiology and Immunology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America.
Ward BM; Department of Dermatology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America.
Norbury CC; Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America.

PLoS Pathog ; 15(10): e1007778, 2019 10.

Article in En | MEDLINE | ID: mdl-31603920

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vaccinia / Vaccinia virus / Interferon Type I / Viral Load / Chemokine CCL4 / Membrane Proteins / Nucleotidyltransferases Limits: Animals Language: En Journal: PLoS Pathog Year: 2019 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

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