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Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors.
Kufareva, Irina; Bestgen, Benoit; Brear, Paul; Prudent, Renaud; Laudet, Béatrice; Moucadel, Virginie; Ettaoussi, Mohamed; Sautel, Celine F; Krimm, Isabelle; Engel, Matthias; Filhol, Odile; Borgne, Marc Le; Lomberget, Thierry; Cochet, Claude; Abagyan, Ruben.
Affiliation
  • Kufareva I; University of California, San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences, La Jolla, CA, 92093, USA.
  • Bestgen B; Université de Lyon, Université Claude Bernard Lyon 1, Faculté de Pharmacie - ISPB, EA 4446 Bioactive Molecules and Medicinal Chemistry, 8 avenue Rockefeller, F-69373, Lyon, cedex 8, France.
  • Brear P; Pharmaceutical and Medicinal Chemistry, Saarland University, Campus C2.3, D-66123, Saarbrücken, Germany.
  • Prudent R; Univ. Grenoble Alpes, Inserm U1036, CEA, BCI Laboratory, IRIG, F-38000, Grenoble, France.
  • Laudet B; Ecrins Therapeutics, 5 Avenue du Grand Sablon, 38700, La Tronche, France.
  • Moucadel V; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK.
  • Ettaoussi M; Univ. Grenoble Alpes, Inserm U1036, CEA, BCI Laboratory, IRIG, F-38000, Grenoble, France.
  • Sautel CF; Cellipse MINATEC, 7 Parvis Louis Néel, 38000, Grenoble, cedex 9, France.
  • Krimm I; Univ. Grenoble Alpes, Inserm U1036, CEA, BCI Laboratory, IRIG, F-38000, Grenoble, France.
  • Engel M; CHU Toulouse, Emergency Department, F-31000, Toulouse, France.
  • Filhol O; Univ. Grenoble Alpes, Inserm U1036, CEA, BCI Laboratory, IRIG, F-38000, Grenoble, France.
  • Borgne ML; BioMérieux SA, Centre Christophe Mérieux, 5 rue des Berges, 38024, Grenoble, cedex 1, France.
  • Lomberget T; Université de Lyon, Université Claude Bernard Lyon 1, Faculté de Pharmacie - ISPB, EA 4446 Bioactive Molecules and Medicinal Chemistry, 8 avenue Rockefeller, F-69373, Lyon, cedex 8, France.
  • Cochet C; Univ. Grenoble Alpes, Inserm U1036, CEA, BCI Laboratory, IRIG, F-38000, Grenoble, France.
  • Abagyan R; DERMADIS, 218 avenue Marie Curie, 74160, Archamps, France.
Sci Rep ; 9(1): 15893, 2019 11 04.
Article in En | MEDLINE | ID: mdl-31685885
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Holoenzymes / Casein Kinase II / Protein Kinase Inhibitors Type of study: Guideline / Prognostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2019 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Holoenzymes / Casein Kinase II / Protein Kinase Inhibitors Type of study: Guideline / Prognostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2019 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido