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RITA requires eIF2α-dependent modulation of mRNA translation for its anti-cancer activity.
Ristau, Johannes; van Hoef, Vincent; Peuget, Sylvain; Zhu, Jiawei; Guan, Bo-Jhih; Liang, Shuo; Hatzoglou, Maria; Topisirovic, Ivan; Selivanova, Galina; Larsson, Ola.
Affiliation
  • Ristau J; Department of Onkology-Pathology, Science for Life Laboratories, Karolinska Institutet, Stockholm, Sweden.
  • van Hoef V; Department of Onkology-Pathology, Science for Life Laboratories, Karolinska Institutet, Stockholm, Sweden.
  • Peuget S; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Zhu J; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Guan BJ; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, USA.
  • Liang S; Department of Onkology-Pathology, Science for Life Laboratories, Karolinska Institutet, Stockholm, Sweden.
  • Hatzoglou M; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, USA.
  • Topisirovic I; Lady Davis Institute, SMBD JGH and Gerald Bronfman Department of Oncology, McGill University, Montreal, QC, Canada.
  • Selivanova G; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Larsson O; Department of Onkology-Pathology, Science for Life Laboratories, Karolinska Institutet, Stockholm, Sweden. Ola.Larsson@ki.se.
Cell Death Dis ; 10(11): 845, 2019 11 07.
Article in En | MEDLINE | ID: mdl-31699971
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Biosynthesis / Breast Neoplasms / RNA, Messenger / Eukaryotic Initiation Factor-2 / Gene Expression Regulation, Neoplastic / Tumor Suppressor Protein p53 / DNA-Binding Proteins / Neoplasm Proteins Limits: Female / Humans Language: En Journal: Cell Death Dis Year: 2019 Document type: Article Affiliation country: Suecia Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Biosynthesis / Breast Neoplasms / RNA, Messenger / Eukaryotic Initiation Factor-2 / Gene Expression Regulation, Neoplastic / Tumor Suppressor Protein p53 / DNA-Binding Proteins / Neoplasm Proteins Limits: Female / Humans Language: En Journal: Cell Death Dis Year: 2019 Document type: Article Affiliation country: Suecia Country of publication: Reino Unido