The Role of 18F-FDG PET/CT in Suspected Intraocular Sarcoidosis and Tuberculosis.
Ocul Immunol Inflamm
; 29(3): 530-536, 2021 Apr 03.
Article
in En
| MEDLINE
| ID: mdl-31743044
ABSTRACT
Purpose:
To determine the utility of fluorine-18 fluorodeoxyglucose Positron Emission Tomography Computed Tomography (FDG PET/CT) in patients with suspected ocular sarcoidosis (OS) or intraocular tuberculosis (IOTB) in a resource-constrained, TB endemic area.Methods:
Independent review of the FDG PET/CTs, Computed Tomography (CT) scans and chest radiographs (CXRs) of patients with suspected OS or IOTB and inconclusive conventional workup.Results:
Twenty-nine PET/CTs and CXRs were reviewed, with 38% of PET/CTs and CTs demonstrating evidence of TB or sarcoidosis, compared to 21% of CXRs. The sensitivity, specificity, positive and negative predictive values for PET/CT and CT were similar - 85.7%, 95.5%, 85.7% and 95.5% for OS, and 33.3%, 100%, 100% and 68% for IOTB respectively and for CXR, 57.1%, 100%, 100% and 88% for OS, and 16.7%, 100%, 100% and 63% for IOTB.Conclusion:
PET/CT added no significant additional benefit over Chest CT in patients with suspected OS or IOTB.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sarcoidosis
/
Tuberculosis, Pulmonary
/
Radiopharmaceuticals
/
Fluorodeoxyglucose F18
/
Eye Diseases
/
Positron Emission Tomography Computed Tomography
Type of study:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Ocul Immunol Inflamm
Journal subject:
ALERGIA E IMUNOLOGIA
/
OFTALMOLOGIA
Year:
2021
Document type:
Article
Affiliation country:
Sudáfrica