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EC313-a tissue selective SPRM reduces the growth and proliferation of uterine fibroids in a human uterine fibroid tissue xenograft model.
Nair, Hareesh B; Santhamma, Bindu; Dileep, Kalarickal V; Binkley, Peter; Acosta, Kirk; Zhang, Kam Y J; Schenken, Robert; Nickisch, Klaus.
Affiliation
  • Nair HB; Evestra, Inc, 14805 Omicron Drive, San Antonio, TX, 78245, USA. hnair@evestra.com.
  • Santhamma B; Evestra, Inc, 14805 Omicron Drive, San Antonio, TX, 78245, USA.
  • Dileep KV; Laboratory for Structural Bioinformatics, Center for Biosystems Dynamics Research, RIKEN, Yokohama, Kanagawa, 230-0045, Japan.
  • Binkley P; Department of Obstetrics and Gynecology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas, 78229, USA.
  • Acosta K; Evestra, Inc, 14805 Omicron Drive, San Antonio, TX, 78245, USA.
  • Zhang KYJ; Laboratory for Structural Bioinformatics, Center for Biosystems Dynamics Research, RIKEN, Yokohama, Kanagawa, 230-0045, Japan.
  • Schenken R; Department of Obstetrics and Gynecology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas, 78229, USA.
  • Nickisch K; Evestra, Inc, 14805 Omicron Drive, San Antonio, TX, 78245, USA.
Sci Rep ; 9(1): 17279, 2019 11 21.
Article in En | MEDLINE | ID: mdl-31754172

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uterine Neoplasms / Receptors, Progesterone / Contraceptive Agents, Female / Progesterone Congeners / Cell Proliferation / Leiomyoma Limits: Animals / Female / Humans Language: En Journal: Sci Rep Year: 2019 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uterine Neoplasms / Receptors, Progesterone / Contraceptive Agents, Female / Progesterone Congeners / Cell Proliferation / Leiomyoma Limits: Animals / Female / Humans Language: En Journal: Sci Rep Year: 2019 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido