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Helicobacter Pylori Detected in Tap Water of Peruvian Patients with Gastric Cancer.
Castillo, Miluska; Bernabe, Luis; Castaneda, Carlos A; Chavez, Ivan; Ruiz, Eloy; Barreda, Fernando; Valdivia, Daniel; Suarez, Nancy; Nieves, Jais; Dias-Neto, Emmanuel; Boehnke, Kevin; Landa-Baella, Maria P; Montenegro, Paola.
Affiliation
  • Castillo M; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
  • Bernabe L; Universidad Científica del Sur, Peru.
  • Castaneda CA; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
  • Chavez I; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
  • Ruiz E; Universidad Científica del Sur, Peru.
  • Barreda F; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
  • Valdivia D; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
  • Suarez N; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
  • Nieves J; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
  • Dias-Neto E; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
  • Boehnke K; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
  • Landa-Baella MP; CIPE, A.C.Camargo Cancer Center, São Paulo, Brazil.
  • Montenegro P; University of Michigan, Ann Arbor, Michigan, USA.
Asian Pac J Cancer Prev ; 20(11): 3193-3196, 2019 Nov 01.
Article in En | MEDLINE | ID: mdl-31759341
ABSTRACT

OBJECTIVE:

To evaluate the correlation between the presence of H. pylori in paired samples of tap water and gastric cancer (GC) lesion in Lima city (Peru). MATERIAL AND

METHODS:

Gastric tissue and tap-water samples were prospectively collected from 82 Gastric Cancer who lived in Lima. HspA and ureA genes were evaluated by qPCR in the samples. 

Results:

The median age of patients with GC was 63 years, 52.4% were men and stage-II in 36.6%. A home-living time> 10 years was reported in 84.1% of patients. Boiling water treatment was indicated in 85.4% of cases. H. pylori was detected in 69.5% of gastric tissues and in 12.2% of analyzed tap-water. There was no differences in gastric infection rates among those with or without water contamination (70% vs. 69.4%, p=0.971). Conclusion & Impact H. pylori was found in tap-water samples, however, detection rates were lower than in gastric cancer samples. Other sources of infection transmission should be investigated.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach Neoplasms / Water Microbiology / Water Supply / Adenocarcinoma / Helicobacter pylori / Helicobacter Infections Type of study: Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Country/Region as subject: America do sul / Peru Language: En Journal: Asian Pac J Cancer Prev Journal subject: NEOPLASIAS Year: 2019 Document type: Article Affiliation country: Perú Publication country: TAILANDIA / TAILÂNDIA / TH / THAILAND

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach Neoplasms / Water Microbiology / Water Supply / Adenocarcinoma / Helicobacter pylori / Helicobacter Infections Type of study: Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Country/Region as subject: America do sul / Peru Language: En Journal: Asian Pac J Cancer Prev Journal subject: NEOPLASIAS Year: 2019 Document type: Article Affiliation country: Perú Publication country: TAILANDIA / TAILÂNDIA / TH / THAILAND