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Global skin gene expression analysis of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive inflammatory profile.
Skaug, Brian; Khanna, Dinesh; Swindell, William R; Hinchcliff, Monique E; Frech, Tracy M; Steen, Virginia D; Hant, Faye N; Gordon, Jessica K; Shah, Ami A; Zhu, Lisha; Zheng, W Jim; Browning, Jeffrey L; Barron, Alexander M S; Wu, Minghua; Visvanathan, Sudha; Baum, Patrick; Franks, Jennifer M; Whitfield, Michael L; Shanmugam, Victoria K; Domsic, Robyn T; Castelino, Flavia V; Bernstein, Elana J; Wareing, Nancy; Lyons, Marka A; Ying, Jun; Charles, Julio; Mayes, Maureen D; Assassi, Shervin.
Affiliation
  • Skaug B; Division of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas, USA brian.a.skaug@uth.tmc.edu.
  • Khanna D; Scleroderma Program, Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan, USA.
  • Swindell WR; Ohio University Heritage College of Osteopathic Medicine, Athens, Ohio, USA.
  • Hinchcliff ME; Department of Internal Medicine, The Jewish Hospital, Cincinnati, Ohio, USA.
  • Frech TM; Department of Medicine, Section of Allergy, Rheumatology, and Immunology, Yale University, New Haven, Connecticut, USA.
  • Steen VD; Division of Rheumatology, Department of Internal Medicine, University of Utah and Salt Lake Regional Veterans Affairs Medical Center, Salt Lake City, Utah, USA.
  • Hant FN; Division of Rheumatology, Department of Medicine, MedStar Georgetown University Hospital, Washington, DC, USA.
  • Gordon JK; Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA.
  • Shah AA; Department of Rheumatology, Hospital for Special Surgery, New York City, New York, USA.
  • Zhu L; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Zheng WJ; School of Biomedical Informatics, University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Browning JL; School of Biomedical Informatics, University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Barron AMS; Department of Microbiology, Section of Rheumatology, Boston University School of Medicine, Boston, Massachusetts, USA.
  • Wu M; Department of Microbiology, Section of Rheumatology, Boston University School of Medicine, Boston, Massachusetts, USA.
  • Visvanathan S; Division of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Baum P; Boehringer Ingelheim Pharmaceuticals Inc, Ridgefield, Connecticut, USA.
  • Franks JM; Boehringer Ingelheim International GmbH, Biberach, Germany.
  • Whitfield ML; Department of Biomedical Data Science, Dartmouth College Geisel School of Medicine, Lebanon, New Hampshire, USA.
  • Shanmugam VK; Department of Molecular and Systems Biology, Dartmouth College Geisel School of Medicine, Hanover, New Hampshire, USA.
  • Domsic RT; Department of Biomedical Data Science, Dartmouth College Geisel School of Medicine, Lebanon, New Hampshire, USA.
  • Castelino FV; Department of Molecular and Systems Biology, Dartmouth College Geisel School of Medicine, Hanover, New Hampshire, USA.
  • Bernstein EJ; Division of Rheumatology, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
  • Wareing N; Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Lyons MA; Division of Rheumatology, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Ying J; Division of Rheumatology, Vagelos College of Physicians and Surgeons, New York City, New York, USA.
  • Charles J; Division of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Mayes MD; Division of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Assassi S; Division of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas, USA.
Ann Rheum Dis ; 79(3): 379-386, 2020 03.
Article in En | MEDLINE | ID: mdl-31767698
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Scleroderma, Diffuse / Adaptive Immunity / Immunity, Innate Type of study: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Ann Rheum Dis Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Scleroderma, Diffuse / Adaptive Immunity / Immunity, Innate Type of study: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Ann Rheum Dis Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido