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Anhydroecgonine methyl ester (AEME), a cocaine pyrolysis product, impairs glutathione-related enzymes response and increases lipid peroxidation in the hippocampal cell culture.
Garcia, Raphael Caio Tamborelli; Torres, Larissa Lobo; Dati, Livia Mendonça Munhoz; Loureiro, Ana Paula de Melo; Afeche, Solange Castro; Sandoval, Maria Regina Lopes; Marcourakis, Tania.
Affiliation
  • Garcia RCT; Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bl. 13B, 05508-000 São Paulo, SP, Brazil.
  • Torres LL; Department of Pharmaceutical Sciences, Institute of Environmental, Chemical and Pharmaceutical Sciences, Federal University of São Paulo, Rua São Nicolau, 210, 1° andar, 09913-030 Diadema, SP, Brazil.
  • Dati LMM; Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bl. 13B, 05508-000 São Paulo, SP, Brazil.
  • Loureiro APM; Department of Food and Drugs, School of Pharmaceutical Sciences, Federal University of Alfenas, Rua Gabriel Monteiro da Silva, 700, 37130-001 Alfenas, MG, Brazil.
  • Afeche SC; Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bl. 13B, 05508-000 São Paulo, SP, Brazil.
  • Sandoval MRL; Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, Bl. 13B, 05508-000 São Paulo, SP, Brazil.
  • Marcourakis T; Laboratory of Pharmacology, Butantan Institute, Av. Vital Brasil, 1500, 05503-900, São Paulo, SP, Brazil.
Toxicol Rep ; 6: 1223-1229, 2019.
Article in En | MEDLINE | ID: mdl-31768333
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Toxicol Rep Year: 2019 Document type: Article Affiliation country: Brasil Country of publication: Irlanda
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Toxicol Rep Year: 2019 Document type: Article Affiliation country: Brasil Country of publication: Irlanda