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Semi-Synthetic Ingenol Derivative from Euphorbia tirucalli Inhibits Protein Kinase C Isotypes and Promotes Autophagy and S-phase Arrest on Glioma Cell Lines.
Silva, Viviane Aline Oliveira; Rosa, Marcela Nunes; Tansini, Aline; Martinho, Olga; Tanuri, Amilcar; Evangelista, Adriane Feijó; Cruvinel Carloni, Adriana; Lima, João Paulo; Pianowski, Luiz Francisco; Reis, Rui Manuel.
Affiliation
  • Silva VAO; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, São Paulo 14784-400, Brazil.
  • Rosa MN; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, São Paulo 14784-400, Brazil.
  • Tansini A; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, São Paulo 14784-400, Brazil.
  • Martinho O; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, São Paulo 14784-400, Brazil.
  • Tanuri A; Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710-057 Braga, Portugal.
  • Evangelista AF; ICVS/3B's-PT Government Associate Laboratory, 4806-909 Braga/Guimarães, Portugal.
  • Cruvinel Carloni A; Laboratory of Molecular Virology, Departaments of genetics, IB, Federal University of Rio de Janeiro, Rio de Janeiro 21941-902, Brazil.
  • Lima JP; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, São Paulo 14784-400, Brazil.
  • Pianowski LF; Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, São Paulo 14784-400, Brazil.
  • Reis RM; Medical Oncology, Barretos Cancer Hospital, Barretos, São Paulo 14784-400, Brazil.
Molecules ; 24(23)2019 Nov 22.
Article in En | MEDLINE | ID: mdl-31771098
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Protein Kinase C / Euphorbia / Diterpenes / Glioma / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2019 Document type: Article Affiliation country: Brasil
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Protein Kinase C / Euphorbia / Diterpenes / Glioma / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2019 Document type: Article Affiliation country: Brasil