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Dienogest regulates apoptosis, proliferation, and invasiveness of endometriotic cyst stromal cells via endoplasmic reticulum stress induction.
Choi, JongYeob; Jo, MinWha; Lee, EunYoung; Lee, Dong-Yun; Choi, DooSeok.
Affiliation
  • Choi J; Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul 06351, Korea.
  • Jo M; Center for Clinical Research, Samsung Biomedical Research Institute, 50 Irwon-dong, Gangnam-gu, Seoul 06351, Korea.
  • Lee E; Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul 06351, Korea.
  • Lee DY; Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul 06351, Korea.
  • Choi D; Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul 06351, Korea.
Mol Hum Reprod ; 26(1): 30-39, 2020 01 01.
Article in En | MEDLINE | ID: mdl-31814016
Subject(s)
Cysts/drug therapy; Endometriosis/drug therapy; Endoplasmic Reticulum Stress/drug effects; Hormone Antagonists/pharmacology; Nandrolone/analogs & derivatives; Transcription Factor CHOP/genetics; eIF-2 Kinase/genetics; Activating Transcription Factor 4/genetics; Activating Transcription Factor 4/metabolism; Adult; Apoptosis/drug effects; Cell Movement/drug effects; Cell Proliferation/drug effects; Cysts/genetics; Cysts/metabolism; Cysts/pathology; Endometriosis/genetics; Endometriosis/metabolism; Endometriosis/pathology; Endometrium/drug effects; Endometrium/metabolism; Endometrium/pathology; Endoplasmic Reticulum/drug effects; Endoplasmic Reticulum/genetics; Endoplasmic Reticulum/metabolism; Endoribonucleases/antagonists & inhibitors; Endoribonucleases/genetics; Endoribonucleases/metabolism; Female; Gene Expression Regulation; Humans; MAP Kinase Kinase Kinase 5/genetics; MAP Kinase Kinase Kinase 5/metabolism; MAP Kinase Signaling System; Nandrolone/pharmacology; Progesterone/pharmacology; Protein Serine-Threonine Kinases/antagonists & inhibitors; Protein Serine-Threonine Kinases/genetics; Protein Serine-Threonine Kinases/metabolism; RNA, Small Interfering/genetics; RNA, Small Interfering/metabolism; Stromal Cells/drug effects; Stromal Cells/metabolism; Stromal Cells/pathology; TNF Receptor-Associated Factor 2/genetics; TNF Receptor-Associated Factor 2/metabolism; Transcription Factor CHOP/agonists; Transcription Factor CHOP/metabolism; eIF-2 Kinase/antagonists & inhibitors; eIF-2 Kinase/metabolism
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: EIF-2 Kinase / Cysts / Endometriosis / Transcription Factor CHOP / Endoplasmic Reticulum Stress / Hormone Antagonists / Nandrolone Language: En Journal: Mol Hum Reprod Journal subject: BIOLOGIA MOLECULAR / MEDICINA REPRODUTIVA Year: 2020 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: EIF-2 Kinase / Cysts / Endometriosis / Transcription Factor CHOP / Endoplasmic Reticulum Stress / Hormone Antagonists / Nandrolone Language: En Journal: Mol Hum Reprod Journal subject: BIOLOGIA MOLECULAR / MEDICINA REPRODUTIVA Year: 2020 Document type: Article