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In Chronic Lymphocytic Leukemia the JAK2/STAT3 Pathway Is Constitutively Activated and Its Inhibition Leads to CLL Cell Death Unaffected by the Protective Bone Marrow Microenvironment.
Severin, Filippo; Frezzato, Federica; Visentin, Andrea; Martini, Veronica; Trimarco, Valentina; Carraro, Samuela; Tibaldi, Elena; Brunati, Anna Maria; Piazza, Francesco; Semenzato, Gianpietro; Facco, Monica; Trentin, Livio.
Affiliation
  • Severin F; Department of Medicine-DIMED, Hematology and Clinical Immunology Unit, University of Padua, 35128 Padua, Italy.
  • Frezzato F; Veneto Institute of Molecular Medicine, 35128 Padua, Italy.
  • Visentin A; Department of Medicine-DIMED, Hematology and Clinical Immunology Unit, University of Padua, 35128 Padua, Italy.
  • Martini V; Veneto Institute of Molecular Medicine, 35128 Padua, Italy.
  • Trimarco V; Department of Medicine-DIMED, Hematology and Clinical Immunology Unit, University of Padua, 35128 Padua, Italy.
  • Carraro S; Veneto Institute of Molecular Medicine, 35128 Padua, Italy.
  • Tibaldi E; Department of Medicine-DIMED, Hematology and Clinical Immunology Unit, University of Padua, 35128 Padua, Italy.
  • Brunati AM; Veneto Institute of Molecular Medicine, 35128 Padua, Italy.
  • Piazza F; Department of Medicine-DIMED, Hematology and Clinical Immunology Unit, University of Padua, 35128 Padua, Italy.
  • Semenzato G; Veneto Institute of Molecular Medicine, 35128 Padua, Italy.
  • Facco M; Department of Medicine-DIMED, Hematology and Clinical Immunology Unit, University of Padua, 35128 Padua, Italy.
  • Trentin L; Department of Molecular Medicine-DMM, University of Padua, 35128 Padua, Italy.
Cancers (Basel) ; 11(12)2019 Dec 04.
Article in En | MEDLINE | ID: mdl-31817171
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cancers (Basel) Year: 2019 Document type: Article Affiliation country: Italia Country of publication: Suiza
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cancers (Basel) Year: 2019 Document type: Article Affiliation country: Italia Country of publication: Suiza