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A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism.
Davidsson, Marcus; Wang, Gang; Aldrin-Kirk, Patrick; Cardoso, Tiago; Nolbrant, Sara; Hartnor, Morgan; Mudannayake, Janitha; Parmar, Malin; Björklund, Tomas.
Affiliation
  • Davidsson M; Molecular Neuromodulation, Department of Experimental Medical Science, Lund University, 221 84 Lund, Sweden.
  • Wang G; Molecular Neuromodulation, Department of Experimental Medical Science, Lund University, 221 84 Lund, Sweden.
  • Aldrin-Kirk P; Molecular Neuromodulation, Department of Experimental Medical Science, Lund University, 221 84 Lund, Sweden.
  • Cardoso T; Developmental and Regenerative Neurobiology, Department of Experimental Medical Science, Lund Stem Cell Center, Lund University, 221 84 Lund, Sweden.
  • Nolbrant S; Developmental and Regenerative Neurobiology, Department of Experimental Medical Science, Lund Stem Cell Center, Lund University, 221 84 Lund, Sweden.
  • Hartnor M; Molecular Neuromodulation, Department of Experimental Medical Science, Lund University, 221 84 Lund, Sweden.
  • Mudannayake J; Molecular Neuromodulation, Department of Experimental Medical Science, Lund University, 221 84 Lund, Sweden.
  • Parmar M; Developmental and Regenerative Neurobiology, Department of Experimental Medical Science, Lund Stem Cell Center, Lund University, 221 84 Lund, Sweden.
  • Björklund T; Molecular Neuromodulation, Department of Experimental Medical Science, Lund University, 221 84 Lund, Sweden.
Proc Natl Acad Sci U S A ; 116(52): 27053-27062, 2019 Dec 26.
Article in En | MEDLINE | ID: mdl-31818949

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Proc Natl Acad Sci U S A Year: 2019 Document type: Article Affiliation country: Suecia Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Proc Natl Acad Sci U S A Year: 2019 Document type: Article Affiliation country: Suecia Country of publication: Estados Unidos