Different Roles of Human Cytochrome P450 2C9 and 3A Enzymes in Diclofenac 4'- and 5-Hydroxylations Mediated by Metabolically Inactivated Human Hepatocytes in Previously Transplanted Chimeric Mice.
Chem Res Toxicol
; 33(2): 634-639, 2020 02 17.
Article
in En
| MEDLINE
| ID: mdl-31854189
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Diclofenac
/
Transplantation Chimera
/
Hepatocytes
/
Cytochrome P-450 CYP3A
/
Cytochrome P-450 CYP2C9
Limits:
Animals
/
Humans
Language:
En
Journal:
Chem Res Toxicol
Journal subject:
TOXICOLOGIA
Year:
2020
Document type:
Article
Affiliation country:
Japón