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DP1 Activation Reverses Age-Related Hypertension Via NEDD4L-Mediated T-Bet Degradation in T Cells.
Kong, Deping; Wan, Qiangyou; Li, Juanjuan; Zuo, Shengkai; Liu, Guizhu; Liu, Qian; Wang, Chenchen; Bai, Peiyuan; Duan, Sheng-Zhong; Zhou, Bin; Gounari, Fotini; Lyu, Ankang; Lazarus, Michael; Breyer, Richard M; Yu, Ying.
Affiliation
  • Kong D; Department of Pharmacology and Tianjin Key Laboratory of Inflammatory Biology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), School of Basic Medical Sciences, Tianjin Medical University, China (D.K., S.Z., Q.L., Y.Y.).
  • Wan Q; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences (Q.W., C.W., Y.Y.), University of Chinese Academy of Sciences, Chinese Academy of Sciences, China.
  • Li J; Department of Gastroenterology (J.L.), Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China.
  • Zuo S; Department of Pharmacology and Tianjin Key Laboratory of Inflammatory Biology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), School of Basic Medical Sciences, Tianjin Medical University, China (D.K., S.Z., Q.L., Y.Y.).
  • Liu G; National Clinical Research Center for Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, China (G.L., Y.Y.).
  • Liu Q; Department of Pharmacology and Tianjin Key Laboratory of Inflammatory Biology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), School of Basic Medical Sciences, Tianjin Medical University, China (D.K., S.Z., Q.L., Y.Y.).
  • Wang C; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences (Q.W., C.W., Y.Y.), University of Chinese Academy of Sciences, Chinese Academy of Sciences, China.
  • Bai P; Department of Cardiology (P.B., A.L.), Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China.
  • Duan SZ; Laboratory of Oral Microbiology, Shanghai Research Institute of Stomatology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, China (S.-Z.D.).
  • Zhou B; State Key Laboratory of Cell Biology, Chinese Academy of Sciences Center for Excellence on Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology (B.Z.), University of Chinese Academy of Sciences, Chinese Academy of Sciences, China.
  • Gounari F; Division of Rheumatology and Knapp Center for Lupus and Immunology Research, University of Chicago, IL (F.G.).
  • Lyu A; Department of Cardiology (P.B., A.L.), Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China.
  • Lazarus M; International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba City, Ibaraki, Japan (M.L.).
  • Breyer RM; Department of Veterans Affairs, Tennessee Valley Health Authority, and Department of Medicine, Vanderbilt University Medical Center, Nashville, TN (R.M.B.).
  • Yu Y; Department of Pharmacology and Tianjin Key Laboratory of Inflammatory Biology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), School of Basic Medical Sciences, Tianjin Medical University, China (D.K., S.Z., Q.L., Y.Y.).
Circulation ; 141(8): 655-666, 2020 02 25.
Article in En | MEDLINE | ID: mdl-31893939
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Receptors, Prostaglandin / CD4-Positive T-Lymphocytes / T-Box Domain Proteins / Nedd4 Ubiquitin Protein Ligases Limits: Aged / Animals / Humans Language: En Journal: Circulation Year: 2020 Document type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Receptors, Prostaglandin / CD4-Positive T-Lymphocytes / T-Box Domain Proteins / Nedd4 Ubiquitin Protein Ligases Limits: Aged / Animals / Humans Language: En Journal: Circulation Year: 2020 Document type: Article