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Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy.
Affronti, Hayley C; Rowsam, Aryn M; Pellerite, Anthony J; Rosario, Spencer R; Long, Mark D; Jacobi, Justine J; Bianchi-Smiraglia, Anna; Boerlin, Christoph S; Gillard, Bryan M; Karasik, Ellen; Foster, Barbara A; Moser, Michael; Wilton, John H; Attwood, Kristopher; Nikiforov, Mikhail A; Azabdaftari, Gissou; Pili, Roberto; Phillips, James G; Casero, Robert A; Smiraglia, Dominic J.
Affiliation
  • Affronti HC; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Rowsam AM; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Pellerite AJ; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Rosario SR; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Long MD; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Jacobi JJ; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Bianchi-Smiraglia A; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Boerlin CS; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Gillard BM; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Karasik E; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Foster BA; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Moser M; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Wilton JH; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Attwood K; Department of Biostatistics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Nikiforov MA; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Azabdaftari G; Department of Pathology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
  • Pili R; Department of Hematology and Oncology, Indiana University, Indianapolis, IN, USA.
  • Phillips JG; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
  • Casero RA; The Sydney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, 21231, USA.
  • Smiraglia DJ; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA. Dominic.Smiraglia@roswellpark.org.
Nat Commun ; 11(1): 52, 2020 01 07.
Article in En | MEDLINE | ID: mdl-31911608
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyamines / Prostatic Neoplasms / Methionine Limits: Animals / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyamines / Prostatic Neoplasms / Methionine Limits: Animals / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido