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Dexamethasone inhibits respiratory syncytial virus-driven mucus production while increasing viral replication without altering antiviral interferon signaling.
McAllister, Christopher S; Ansaldi, Dan; Growcott, Ellena J; Zhong, Yang; Quackenbush, Doug; Wolff, Karen C; Chen, Zhong; Tanaseichuk, Olga; Lelais, Gerald; Barnes, S Whitney; Federe, Glenn C; Luna, Fabio; Walker, John R; Zhou, Yingyao; Kuhen, Kelli L.
Affiliation
  • McAllister CS; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA. Electronic address: cmcallister@gnf.org.
  • Ansaldi D; Novartis Institute for BioMedical Research, Emeryville, CA, USA.
  • Growcott EJ; Novartis Institute for BioMedical Research, Emeryville, CA, USA.
  • Zhong Y; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Quackenbush D; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Wolff KC; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Chen Z; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Tanaseichuk O; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Lelais G; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Barnes SW; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Federe GC; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Luna F; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Walker JR; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Zhou Y; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
  • Kuhen KL; Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.
Virology ; 540: 195-206, 2020 01 15.
Article in En | MEDLINE | ID: mdl-31929001
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Virus Replication / Dexamethasone / Signal Transduction / Interferons / Respiratory Syncytial Virus, Human / Respiratory Syncytial Virus Infections / Mucus Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Virology Year: 2020 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Virus Replication / Dexamethasone / Signal Transduction / Interferons / Respiratory Syncytial Virus, Human / Respiratory Syncytial Virus Infections / Mucus Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Virology Year: 2020 Document type: Article Country of publication: Estados Unidos