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Single-molecule imaging reveals the oligomeric state of functional TNFα-induced plasma membrane TNFR1 clusters in cells.
Karathanasis, Christos; Medler, Juliane; Fricke, Franziska; Smith, Sonja; Malkusch, Sebastian; Widera, Darius; Fulda, Simone; Wajant, Harald; van Wijk, Sjoerd J L; Dikic, Ivan; Heilemann, Mike.
Affiliation
  • Karathanasis C; Institute of Physical and Theoretical Chemistry, Goethe University, Max-von-Laue-Strasse 7, 60438 Frankfurt am Main, Germany.
  • Medler J; Division of Molecular Internal Medicine, Department of Internal Medicine II, University Hospital Würzburg, Auverahaus, Grombühlstrasse 12, 97080 Würzburg, Germany.
  • Fricke F; Institute of Physical and Theoretical Chemistry, Goethe University, Max-von-Laue-Strasse 7, 60438 Frankfurt am Main, Germany.
  • Smith S; Institute for Experimental Cancer Research in Paediatrics, Goethe University, Komturstrasse 3a, 60528 Frankfurt am Main, Germany.
  • Malkusch S; Institute of Physical and Theoretical Chemistry, Goethe University, Max-von-Laue-Strasse 7, 60438 Frankfurt am Main, Germany.
  • Widera D; Stem Cell Biology and Regenerative Medicine Group, School of Pharmacy, University of Reading, RG6 6UB Reading, UK.
  • Fulda S; Institute for Experimental Cancer Research in Paediatrics, Goethe University, Komturstrasse 3a, 60528 Frankfurt am Main, Germany.
  • Wajant H; German Cancer Consortium (DKTK), Heidelberg, Germany.
  • van Wijk SJL; German Cancer Research Centre (DKFZ), Heidelberg, Germany.
  • Dikic I; Division of Molecular Internal Medicine, Department of Internal Medicine II, University Hospital Würzburg, Auverahaus, Grombühlstrasse 12, 97080 Würzburg, Germany.
  • Heilemann M; Institute for Experimental Cancer Research in Paediatrics, Goethe University, Komturstrasse 3a, 60528 Frankfurt am Main, Germany. s.wijk@kinderkrebsstiftung-frankfurt.de ivan.dikic@biochem2.de heilemann@chemie.uni-frankfurt.de.
Sci Signal ; 13(614)2020 01 14.
Article in En | MEDLINE | ID: mdl-31937565
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Membrane / Tumor Necrosis Factor-alpha / Receptors, Tumor Necrosis Factor, Type I / Protein Multimerization / Single Molecule Imaging Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2020 Document type: Article Affiliation country: Alemania Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Membrane / Tumor Necrosis Factor-alpha / Receptors, Tumor Necrosis Factor, Type I / Protein Multimerization / Single Molecule Imaging Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2020 Document type: Article Affiliation country: Alemania Country of publication: Estados Unidos