[Pemphigoid gestationis after egg donation : A case report]. / Pemphigoid gestationis bei Eizellspende : Ein Fallbericht.
Hautarzt
; 71(3): 223-226, 2020 Mar.
Article
in De
| MEDLINE
| ID: mdl-31950210
ABSTRACT
Pemphigoid gestationis (PG) is a blistering autoimmune skin disease, typically occurring in the second and third trimester of pregnancy. Aberrant expression of major histocompatibility complex (MHC) class II molecules on the chorionic villi seems to lead to antibody production against bullous pemphigoid (BP)-180. We report a case of PG in a woman whose pregnancy was achieved using egg donation. Since the entire fetal genome is allogeneic to the mother, augmented immune reaction in egg-donated pregnancies appears to trigger the occurrence of PG.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Autoimmune Diseases
/
Skin Diseases, Vesiculobullous
/
Blister
/
Pemphigoid Gestationis
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Language:
De
Journal:
Hautarzt
Year:
2020
Document type:
Article
Publication country:
ALEMANHA
/
ALEMANIA
/
DE
/
DEUSTCHLAND
/
GERMANY