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The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders.
Andersen, Mette K; Jørsboe, Emil; Skotte, Line; Hanghøj, Kristian; Sandholt, Camilla H; Moltke, Ida; Grarup, Niels; Kern, Timo; Mahendran, Yuvaraj; Søborg, Bolette; Bjerregaard, Peter; Larsen, Christina V L; Dahl-Petersen, Inger K; Tiwari, Hemant K; Feenstra, Bjarke; Koch, Anders; Wiener, Howard W; Hopkins, Scarlett E; Pedersen, Oluf; Melbye, Mads; Boyer, Bert B; Jørgensen, Marit E; Albrechtsen, Anders; Hansen, Torben.
Affiliation
  • Andersen MK; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Jørsboe E; The Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
  • Skotte L; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  • Hanghøj K; The Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
  • Sandholt CH; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Moltke I; The Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
  • Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Kern T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Mahendran Y; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Søborg B; PEPperPRINT GmbH, Heidelberg, Germany.
  • Bjerregaard P; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  • Larsen CVL; National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
  • Dahl-Petersen IK; National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
  • Tiwari HK; Greenland Centre for Health Research, University of Greenland, Nuuk, Greenland.
  • Feenstra B; National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
  • Koch A; Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
  • Wiener HW; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  • Hopkins SE; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  • Pedersen O; Greenland Centre for Health Research, University of Greenland, Nuuk, Greenland.
  • Melbye M; Department of Infectious Diseases, Rigshospitalet University Hospital, Copenhagen, Denmark.
  • Boyer BB; Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
  • Jørgensen ME; Department of Obstetrics and Gynecology, Center for Developmental Health, Knight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon, United States of America.
  • Albrechtsen A; Center for Alaska Native Health Research, University of Alaska Fairbanks, Fairbanks, Alaska, United States of America.
  • Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
PLoS Genet ; 16(1): e1008544, 2020 01.
Article in En | MEDLINE | ID: mdl-31978080
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromosomes, Human, Pair 11 / Inuit / Body Mass Index / Polymorphism, Single Nucleotide Type of study: Risk_factors_studies Limits: Female / Humans / Male Country/Region as subject: America do norte / Europa Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2020 Document type: Article Affiliation country: Dinamarca
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromosomes, Human, Pair 11 / Inuit / Body Mass Index / Polymorphism, Single Nucleotide Type of study: Risk_factors_studies Limits: Female / Humans / Male Country/Region as subject: America do norte / Europa Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2020 Document type: Article Affiliation country: Dinamarca