The inhibitor of apoptosis proteins antagonist Debio 1143 promotes the PD-1 blockade-mediated HIV load reduction in blood and tissues of humanized mice.

Bobardt, Michael; Kuo, Joseph; Chatterji, Udayan; Wiedemann, Norbert; Vuagniaux, Gregoire; Gallay, Philippe

Bobardt, Michael; Kuo, Joseph; Chatterji, Udayan; Wiedemann, Norbert; Vuagniaux, Gregoire; Gallay, Philippe.

Affiliation

Bobardt M; Department of Immunology & Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.
Kuo J; Department of Immunology & Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.
Chatterji U; Department of Immunology & Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.
Wiedemann N; Debiopharm International S.A., Lausanne, Switzerland.
Vuagniaux G; Debiopharm International S.A., Lausanne, Switzerland.
Gallay P; Department of Immunology & Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.

PLoS One ; 15(1): e0227715, 2020.

Article in En | MEDLINE | ID: mdl-31978106

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azocines / Benzhydryl Compounds / HIV Infections / Inhibitor of Apoptosis Proteins / Programmed Cell Death 1 Receptor / Antibodies, Monoclonal Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2020 Document type: Article Affiliation country: Estados Unidos

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