SRSF1-3, a splicing and somatic hypermutation regulator, controls transcription of IgV genes via chromatin regulators SATB2, UBN1 and histone variant H3.3.

Singh, Amit Kumar; Tamrakar, Anubhav; Jaiswal, Ankit; Kanayama, Naoki; Kodgire, Prashant

Singh, Amit Kumar; Tamrakar, Anubhav; Jaiswal, Ankit; Kanayama, Naoki; Kodgire, Prashant.

Affiliation

Singh AK; Discipline of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Indore 453 552, Madhya Pradesh, India.
Tamrakar A; Discipline of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Indore 453 552, Madhya Pradesh, India.
Jaiswal A; Discipline of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Indore 453 552, Madhya Pradesh, India.
Kanayama N; Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Tsushima-Naka, Kita-Ku, Okayama 700-8530, Japan.
Kodgire P; Discipline of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Indore 453 552, Madhya Pradesh, India. Electronic address: pkodgire@iiti.ac.in.

Mol Immunol ; 119: 69-82, 2020 03.

Article in En | MEDLINE | ID: mdl-31986311

Subject(s)
Key words

Activation-induced cytidine deaminase (AID); Histone variant (H3.3); Immunoglobulin (Ig) genes; Somatic hypermutation (SHM); Special AT-rich sequence binding protein 2 (SATB2); Splicing regulator SRSF1-3; ubinuclein1 (UBN1)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Immunoglobulin Variable Region / Genes, Immunoglobulin / Histones / RNA Splicing / Gene Expression Regulation / Serine-Arginine Splicing Factors Limits: Animals Language: En Journal: Mol Immunol Year: 2020 Document type: Article Affiliation country: India Country of publication: Reino Unido

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