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L-Cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling.
Lund, Mari Lilith; Sorrentino, Giovanni; Egerod, Kristoffer Lihme; Kroone, Chantal; Mortensen, Brynjulf; Knop, Filip Krag; Reimann, Frank; Gribble, Fiona M; Drucker, Daniel J; de Koning, Eelco J P; Schoonjans, Kristina; Bäckhed, Fredrik; Schwartz, Thue W; Petersen, Natalia.
Affiliation
  • Lund ML; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Sorrentino G; Laboratory of Metabolic Signaling, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Egerod KL; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Kroone C; Department of Thrombosis and Hemostasis, Leiden University Medical Centre, Leiden, the Netherlands.
  • Mortensen B; Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
  • Knop FK; Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Reimann F; Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
  • Gribble FM; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Drucker DJ; Steno Diabetes Center Copenhagen, Gentofte, Denmark.
  • de Koning EJP; Institute of Metabolic Science and Medical Research Council Metabolic Diseases Unit, University of Cambridge, Addenbrooke's Hospital, Cambridge, U.K.
  • Schoonjans K; Institute of Metabolic Science and Medical Research Council Metabolic Diseases Unit, University of Cambridge, Addenbrooke's Hospital, Cambridge, U.K.
  • Bäckhed F; Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
  • Schwartz TW; Department of Medicine, Leiden University Medical Centre, Leiden, the Netherlands.
  • Petersen N; Hubrecht Institute/Koninklijke Nederlandse Akademie van Wetenschappen (KNAW) and University Medical Center Utrecht, Utrecht, the Netherlands.
Diabetes ; 69(4): 614-623, 2020 04.
Article in En | MEDLINE | ID: mdl-32041793
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bile Acids and Salts / Serotonin / Cell Differentiation / Enteroendocrine Cells / Paracrine Communication / Receptors, G-Protein-Coupled / Glucagon-Like Peptide 1 Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Diabetes Year: 2020 Document type: Article Affiliation country: Dinamarca Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bile Acids and Salts / Serotonin / Cell Differentiation / Enteroendocrine Cells / Paracrine Communication / Receptors, G-Protein-Coupled / Glucagon-Like Peptide 1 Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Diabetes Year: 2020 Document type: Article Affiliation country: Dinamarca Country of publication: Estados Unidos