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Canagliflozin inhibits p-gp function and early autophagy and improves the sensitivity to the antitumor effect of doxorubicin.
Zhong, Jin; Sun, Pengbo; Xu, Naihan; Liao, Meijian; Xu, Chenke; Ding, Yipei; Cai, Jin; Zhang, Yaou; Xie, Weidong.
Affiliation
  • Zhong J; State Key Laboratory of Chemical Oncogenomics, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China; Open FIESTA Center, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China; Key Lab in Health Science and Technology, Div
  • Sun P; State Key Laboratory of Chemical Oncogenomics, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China; Open FIESTA Center, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China; Key Lab in Health Science and Technology, Div
  • Xu N; State Key Laboratory of Chemical Oncogenomics, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China; Open FIESTA Center, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China; Key Lab in Health Science and Technology, Div
  • Liao M; Key Lab in Health Science and Technology, Division of Life Science and Health, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.
  • Xu C; Key Lab in Health Science and Technology, Division of Life Science and Health, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.
  • Ding Y; State Key Laboratory of Chemical Oncogenomics, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China; Key Lab in Health Science and Technology, Division of Life Science and Health, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 5
  • Cai J; Open FIESTA Center, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China; Key Lab in Health Science and Technology, Division of Life Science and Health, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.
  • Zhang Y; State Key Laboratory of Chemical Oncogenomics, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China; Open FIESTA Center, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China; Key Lab in Health Science and Technology, Div
  • Xie W; State Key Laboratory of Chemical Oncogenomics, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China; Open FIESTA Center, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China; Key Lab in Health Science and Technology, Div
Biochem Pharmacol ; 175: 113856, 2020 05.
Article in En | MEDLINE | ID: mdl-32061772
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Doxorubicin / ATP Binding Cassette Transporter, Subfamily B, Member 1 / Drug Resistance, Neoplasm / Canagliflozin / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Biochem Pharmacol Year: 2020 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Doxorubicin / ATP Binding Cassette Transporter, Subfamily B, Member 1 / Drug Resistance, Neoplasm / Canagliflozin / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Biochem Pharmacol Year: 2020 Document type: Article