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Reinstated p53 response and high anti-T-cell leukemia activity by the novel alkylating deacetylase inhibitor tinostamustine.
Pützer, S; Varghese, L; von Jan, J; Braun, T; Giri, A K; Mayer, P; Riet, N; Timonen, S; Oberbeck, S; Kuusanmäki, H; Mustjoki, S; Stern, M-H; Aittokallio, T; Newrzela, S; Schrader, A; Herling, M.
Affiliation
  • Pützer S; Department of Internal Medicine, Center for Integrated Oncology Aachen-Bonn-Cologne-Duesseldorf (CIO ABCD), University of Cologne (UoC), Cologne, Germany.
  • Varghese L; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Cologne, Germany.
  • von Jan J; Center for Molecular Medicine Cologne (CMMC), UoC, Cologne, Germany.
  • Braun T; Department of Internal Medicine, Center for Integrated Oncology Aachen-Bonn-Cologne-Duesseldorf (CIO ABCD), University of Cologne (UoC), Cologne, Germany.
  • Giri AK; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Cologne, Germany.
  • Mayer P; Center for Molecular Medicine Cologne (CMMC), UoC, Cologne, Germany.
  • Riet N; Department of Internal Medicine, Center for Integrated Oncology Aachen-Bonn-Cologne-Duesseldorf (CIO ABCD), University of Cologne (UoC), Cologne, Germany.
  • Timonen S; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Cologne, Germany.
  • Oberbeck S; Center for Molecular Medicine Cologne (CMMC), UoC, Cologne, Germany.
  • Kuusanmäki H; Department of Internal Medicine, Center for Integrated Oncology Aachen-Bonn-Cologne-Duesseldorf (CIO ABCD), University of Cologne (UoC), Cologne, Germany.
  • Mustjoki S; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Cologne, Germany.
  • Stern MH; Center for Molecular Medicine Cologne (CMMC), UoC, Cologne, Germany.
  • Aittokallio T; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Newrzela S; Department of Internal Medicine, Center for Integrated Oncology Aachen-Bonn-Cologne-Duesseldorf (CIO ABCD), University of Cologne (UoC), Cologne, Germany.
  • Schrader A; Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), UoC, Cologne, Germany.
  • Herling M; Center for Molecular Medicine Cologne (CMMC), UoC, Cologne, Germany.
Leukemia ; 34(9): 2513-2518, 2020 09.
Article in En | MEDLINE | ID: mdl-32099034
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / Leukemia, T-Cell / Tumor Suppressor Protein p53 / Antineoplastic Agents, Alkylating / Histone Deacetylase Inhibitors Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2020 Document type: Article Affiliation country: Alemania
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / Leukemia, T-Cell / Tumor Suppressor Protein p53 / Antineoplastic Agents, Alkylating / Histone Deacetylase Inhibitors Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2020 Document type: Article Affiliation country: Alemania