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Metabolic Syndrome and psoriatic arthritis: considerations for the clinician.
Caso, Francesco; Chimenti, Maria Sole; Navarini, Luca; Ruscitti, Piero; Peluso, Rosario; Girolimetto, Nicolò; Del Puente, Antonio; Giacomelli, Roberto; Scarpa, Raffaele; Costa, Luisa.
Affiliation
  • Caso F; Rheumatology Unit, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy.
  • Chimenti MS; Rheumatology, Allergology and Clinical Immunology, Department of System Medicine, University of Rome Tor Vergata, Rome, Italy.
  • Navarini L; Unit of Allergology, Clinical Immunology and Rheumatology, Università Campus Bio-Medico di Roma, Rome, Italy.
  • Ruscitti P; Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • Peluso R; Rheumatology Unit, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy.
  • Girolimetto N; Rheumatology Unit, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy.
  • Del Puente A; Department of Rheumatology, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
  • Giacomelli R; Rheumatology Unit, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy.
  • Scarpa R; Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
  • Costa L; Rheumatology Unit, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy.
Expert Rev Clin Immunol ; 16(4): 409-420, 2020 04.
Article in En | MEDLINE | ID: mdl-32149545
Introduction: Metabolic Syndrome (MetS) is strictly interconnected with systemic inflammation, and increased evidence has described a close link between this condition and Psoriatic Arthritis (PsA).Areas covered: This review summarizes main studies exploring clinical aspects and prevalence of MetS in PsA cohorts. Further, there is accumulating evidence showing shared inflammatory pathways between MetS, its components, and PsA.Expert opinion: The high prevalence of MetS in PsA highlights the need for screening, evaluation, and close monitoring of MetS and its components (namely, diabetes mellitus, obesity, hypertension, and dyslipidemia) in psoriatic patients.Further studies should focus on the pathogenetic link between MetS and PsA. More studies are required to identify appropriate algorithms for the assessment and management of MetS in PsA patients.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Physicians / Cardiovascular Diseases / Arthritis, Psoriatic / Metabolic Syndrome / Inflammation Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Expert Rev Clin Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2020 Document type: Article Affiliation country: Italia Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Physicians / Cardiovascular Diseases / Arthritis, Psoriatic / Metabolic Syndrome / Inflammation Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Expert Rev Clin Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2020 Document type: Article Affiliation country: Italia Country of publication: Reino Unido