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Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1δ kinase inhibitor treatment.
Martínez-González, Loreto; Rodríguez-Cueto, Carmen; Cabezudo, Diego; Bartolomé, Fernando; Andrés-Benito, Pol; Ferrer, Isidro; Gil, Carmen; Martín-Requero, Ángeles; Fernández-Ruiz, Javier; Martínez, Ana; de Lago, Eva.
Affiliation
  • Martínez-González L; Centro de Investigaciones Biológicas Margarita Salas-CSIC, Ramiro de Maeztu 9, 28040, Madrid, Spain.
  • Rodríguez-Cueto C; Instituto Universitario de Investigación en Neuroquímica, Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad Complutense, Madrid, Spain.
  • Cabezudo D; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
  • Bartolomé F; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
  • Andrés-Benito P; Instituto Universitario de Investigación en Neuroquímica, Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad Complutense, Madrid, Spain.
  • Ferrer I; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
  • Gil C; Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), 28041, Madrid, Spain.
  • Martín-Requero Á; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
  • Fernández-Ruiz J; Department of Pathology and Experimental Therapeutics, University of Barcelona, Hospitalet de Llobregat, Barcelona, Spain.
  • Martínez A; Bellvitge University Hospital, IDIBELL (Bellvitge Biomedical Research Centre), Hospitalet de Llobregat, Barcelona, Spain.
  • de Lago E; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Sci Rep ; 10(1): 4449, 2020 03 10.
Article in En | MEDLINE | ID: mdl-32157143
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord / Casein Kinase Idelta / Protein Kinase Inhibitors / DNA-Binding Proteins / Amyotrophic Lateral Sclerosis / Motor Neurons Type of study: Observational_studies / Risk_factors_studies Limits: Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Sci Rep Year: 2020 Document type: Article Affiliation country: España
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord / Casein Kinase Idelta / Protein Kinase Inhibitors / DNA-Binding Proteins / Amyotrophic Lateral Sclerosis / Motor Neurons Type of study: Observational_studies / Risk_factors_studies Limits: Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Sci Rep Year: 2020 Document type: Article Affiliation country: España