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OMTX705, a Novel FAP-Targeting ADC Demonstrates Activity in Chemotherapy and Pembrolizumab-Resistant Solid Tumor Models.
Fabre, Myriam; Ferrer, Cristina; Domínguez-Hormaetxe, Saioa; Bockorny, Bruno; Murias, Laura; Seifert, Oliver; Eisler, Stephan A; Kontermann, Roland E; Pfizenmaier, Klaus; Lee, So Young; Vivanco, María dM; López-Casas, Pedro P; Perea, Sofia; Abbas, Muhammad; Richter, Wolfgang; Simon, Laureano; Hidalgo, Manuel.
Affiliation
  • Fabre M; Oncomatryx Biopharma S.L., Derio, Spain. mfabre@oncomatryx.com mah4006@med.cornell.edu.
  • Ferrer C; Oncomatryx Biopharma S.L., Derio, Spain.
  • Domínguez-Hormaetxe S; Oncomatryx Biopharma S.L., Derio, Spain.
  • Bockorny B; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Murias L; Oncomatryx Biopharma S.L., Derio, Spain.
  • Seifert O; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.
  • Eisler SA; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.
  • Kontermann RE; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.
  • Pfizenmaier K; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.
  • Lee SY; CIC BioGUNE, Derio, Spain.
  • Vivanco MD; CIC BioGUNE, Derio, Spain.
  • López-Casas PP; Gastrointestinal Cancer Clinical Research Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Perea S; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
  • Abbas M; Gastrointestinal Cancer Clinical Research Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Richter W; TUBE Pharmaceuticals, Wien, Austria.
  • Simon L; TUBE Pharmaceuticals, Wien, Austria.
  • Hidalgo M; Oncomatryx Biopharma S.L., Derio, Spain.
Clin Cancer Res ; 26(13): 3420-3430, 2020 07 01.
Article in En | MEDLINE | ID: mdl-32161121
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoconjugates / Drug Resistance, Neoplasm / Membrane Proteins / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2020 Document type: Article
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoconjugates / Drug Resistance, Neoplasm / Membrane Proteins / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2020 Document type: Article