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Design, synthesis, and evaluation of N-phenyl-4-(2-phenylsulfonamido)-benzamides as microtubule-targeting agents in drug-resistant cancer cells, displaying HDAC inhibitory response.
Wu, Wei-Cheng; Liu, Yi-Min; Lin, Mei-Hsiang; Liao, Yu-Hsuan; Lai, Mei-Jung; Chuang, Hsun-Yueh; Hung, To-Yu; Chen, Chun-Han; Liou, Jing-Ping.
Affiliation
  • Wu WC; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taiwan.
  • Liu YM; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taiwan; TMU Biomedical Commercialization Center, Taipei Medical University, Taiwan; Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
  • Lin MH; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taiwan.
  • Liao YH; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taiwan.
  • Lai MJ; TMU Biomedical Commercialization Center, Taipei Medical University, Taiwan.
  • Chuang HY; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taiwan.
  • Hung TY; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taiwan.
  • Chen CH; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Cell Physiology and Molecular Image Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan. Electronic address: brianchc@tmu.edu.tw.
  • Liou JP; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taiwan; TMU Biomedical Commercialization Center, Taipei Medical University, Taiwan; School of Pharmacy, National Defense Medical Center, Taipei, Taiwan. Electronic address: jpl@tmu.edu.tw.
Eur J Med Chem ; 192: 112158, 2020 Apr 15.
Article in En | MEDLINE | ID: mdl-32171161
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzamides / Drug Design / Drug Resistance, Neoplasm / Histone Deacetylase Inhibitors / Histone Deacetylases / Microtubules / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article Affiliation country: Taiwán Country of publication: Francia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzamides / Drug Design / Drug Resistance, Neoplasm / Histone Deacetylase Inhibitors / Histone Deacetylases / Microtubules / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article Affiliation country: Taiwán Country of publication: Francia