Safety, reactogenicity, and immunogenicity of a chimpanzee adenovirus vectored Ebola vaccine in children in Africa: a randomised, observer-blind, placebo-controlled, phase 2 trial.

Tapia, Milagritos D; Sow, Samba O; Mbaye, Khardiata D; Thiongane, Aliou; Ndiaye, Birahim P; Ndour, Cheikh T; Mboup, Souleymane; Keshinro, Babajide; Kinge, Thompson N; Vernet, Guy; Bigna, Jean Joel; Oguche, Stephen; Koram, Kwadwo A; Asante, Kwaku P; Gobert, Patrice; Hogrefe, Wayne R; De Ryck, Iris; Debois, Muriel; Bourguignon, Patricia; Jongert, Erik; Ballou, William R; Koutsoukos, Marguerite; Roman, François

Tapia, Milagritos D; Sow, Samba O; Mbaye, Khardiata D; Thiongane, Aliou; Ndiaye, Birahim P; Ndour, Cheikh T; Mboup, Souleymane; Keshinro, Babajide; Kinge, Thompson N; Vernet, Guy; Bigna, Jean Joel; Oguche, Stephen; Koram, Kwadwo A; Asante, Kwaku P; Gobert, Patrice; Hogrefe, Wayne R; De Ryck, Iris; Debois, Muriel; Bourguignon, Patricia; Jongert, Erik; Ballou, William R; Koutsoukos, Marguerite; Roman, François.

Affiliation

Tapia MD; Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: mtapia@som.umaryland.edu.
Sow SO; Centre pour le Développement des Vaccins, Bamako, Mali.
Mbaye KD; University Cheikh Anta Diop, Dakar, Senegal.
Thiongane A; University Cheikh Anta Diop, Dakar, Senegal.
Ndiaye BP; Le Dantec Laboratory of Bacteriology and Virology, Dakar, Senegal; Institut de Recherche en Santé, de Surveillance Epidemiologique et de Formations, Dakar, Senegal.
Ndour CT; University Cheikh Anta Diop, Dakar, Senegal.
Mboup S; Le Dantec Laboratory of Bacteriology and Virology, Dakar, Senegal; Institut de Recherche en Santé, de Surveillance Epidemiologique et de Formations, Dakar, Senegal.
Keshinro B; Walter Reed Program, Abuja, Nigeria.
Kinge TN; Bamenda Regional Hospital, Bamenda, Cameroon.
Vernet G; Centre Pasteur du Cameroun, Yaounde, Cameroon.
Bigna JJ; Centre Pasteur du Cameroun, Yaounde, Cameroon.
Oguche S; University of Jos and Jos University Teaching Hospital, Jos, Nigeria.
Koram KA; Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra, Ghana.
Asante KP; Kintampo Health Research Centre, Kintampo, Ghana.
Gobert P; Quintiles, La Defense Cedex, France.
Hogrefe WR; Q(2) Solutions, San Juan Capistrano, CA, USA.
De Ryck I; GSK, Wavre, Belgium.
Debois M; GSK, Wavre, Belgium.
Bourguignon P; GSK, Wavre, Belgium.
Jongert E; GSK, Wavre, Belgium.
Ballou WR; GSK, Rockville, MD, USA.
Koutsoukos M; GSK, Wavre, Belgium.
Roman F; GSK, Wavre, Belgium.

Lancet Infect Dis ; 20(6): 719-730, 2020 06.

Article in En | MEDLINE | ID: mdl-32199492

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenoviruses, Simian / Hemorrhagic Fever, Ebola / Ebola Vaccines Type of study: Clinical_trials Limits: Adolescent / Animals / Child / Child, preschool / Female / Humans / Infant / Male Language: En Journal: Lancet Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2020 Document type: Article

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