Functional Improvement After Outpatient Cardiac Rehabilitation in Acute Coronary Syndrome Patients is Not Related to Improvement in Left Ventricular Ejection Fraction.
High Blood Press Cardiovasc Prev
; 27(3): 225-230, 2020 Jun.
Article
in En
| MEDLINE
| ID: mdl-32219669
ABSTRACT
INTRODUCTION:
Cardiac rehabilitation (CR) improves the functional capacity and the prognosis of patients with coronary artery disease.AIM:
Our study was aimed at assessing the relationship between functional improvement (evaluated with 6-min Walk Test-6MWT) and the improvement in left ventricular ejection fraction (LVEF) after CR.METHODS:
We collected data from 249 patients (age 66.79 ± 11.06 years; males 81.52%) with a recent history of Acute Coronary Syndrome that performed CR. The functional improvement after CR was expressed as the Δ between distance covered at the final versus the initial 6-min Walking Test (6-MWT), while LVEF was calculated with transthoracic echocardiogram at the beginning and at the end of the CR.RESULTS:
Patients were divided accordingly to their pre-rehab LVEF (≥ 55% vs < 55%). With superimposable age and baseline 6MWT distance covered (434.58 vs 405.12 m, p = 0.08), the latter group presented higher Δ meter values at 6MWT (167.93 vs 193.97 m, p = 0.018). However, no statistically significant positive correlation between Δ meters and Δ LVEF was found. Moreover, linear regression analyses found that nor baseline LVEF nor Δ LVEF were significant determinants of Δ meters when considering the whole group, with age, basal 6MWT and peak CK-MB as additional covariates in the model.CONCLUSION:
Although it could be expected that an increase in LVEF is related to the functional improvement after CR, no significant correlation was found in our population.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Stroke Volume
/
Ventricular Function, Left
/
Exercise Tolerance
/
Exercise Therapy
/
Acute Coronary Syndrome
/
Ambulatory Care
/
Cardiac Rehabilitation
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Aspects:
Patient_preference
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
High Blood Press Cardiovasc Prev
Year:
2020
Document type:
Article
Affiliation country:
Italia