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Acute type A aortic dissection: Aortic Dissection Detection Risk Score in emergency care - surgical delay because of initial misdiagnosis.
Zaschke, Lisa; Habazettl, Helmut; Thurau, Jana; Matschilles, Christian; Göhlich, Amélie; Montagner, Matteo; Falk, Volkmar; Kurz, Stephan D.
Affiliation
  • Zaschke L; Institute of Physiology, Charité - Universitätsmedizin Berlin, Germany.
  • Habazettl H; Institute for Anaesthesiology, German Heart Center Berlin, Germany.
  • Thurau J; Institute of Physiology, Charité - Universitätsmedizin Berlin, Germany.
  • Matschilles C; Institute of Physiology, Charité - Universitätsmedizin Berlin, Germany.
  • Göhlich A; Institute for Anaesthesiology, German Heart Center Berlin, Germany.
  • Montagner M; Institute of Physiology, Charité - Universitätsmedizin Berlin, Germany.
  • Falk V; Institute for Anaesthesiology, German Heart Center Berlin, Germany.
  • Kurz SD; Institute of Physiology, Charité - Universitätsmedizin Berlin, Germany.
Eur Heart J Acute Cardiovasc Care ; 9(3_suppl): S40-S47, 2020 Oct.
Article in En | MEDLINE | ID: mdl-32223297
BACKGROUND: Acute type A aortic dissection requires immediate surgical treatment, but the correct diagnosis is often delayed. This study aimed to analyse how initial misdiagnosis affected the time intervals before surgical treatment, symptoms associated with correct or incorrect initial diagnosis and the potential of the Aortic Dissection Detection Risk Score to improve the sensitivity of initial diagnosis. METHODS: We conducted a retrospective analysis of 350 patients with acute type A aortic dissection. Patients were divided into two groups: initial misdiagnosis (group 0) and correct initial diagnosis of acute type A aortic dissection (group 1). Symptoms were analysed as predictors for the correct or incorrect initial diagnosis by multivariate analysis. Based on these findings, the Aortic Dissection Detection Risk Score was calculated retrospectively; a result ⩾2 was defined as a positive score. RESULTS: The early suspicion of aortic dissection significantly shortened the median time from pain to surgical correction from 8.6 h in patients with an initial misdiagnosis to 5.5 h in patients with the correct initial diagnosis (p<0.001). Of all acute type A aortic dissection patients, 49% had a positive Aortic Dissection Detection Risk Score. Of all initial misdiagnosed patients, 41% had a positive score (⩾2). The presence of lumbar pain (p<0.001), any paresis (p=0.037) and sweating (p=0.042) was more likely to lead to the correct initial diagnosis. CONCLUSION: An early consideration of acute aortic dissection may reduce the delay of surgical care. The suggested Aortic Dissection Detection Risk Score may be a useful tool to improve the preclinical assessment.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vascular Surgical Procedures / Aortic Aneurysm, Thoracic / Risk Assessment / Emergency Medical Services / Propensity Score / Aortic Dissection Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Eur Heart J Acute Cardiovasc Care Year: 2020 Document type: Article Affiliation country: Alemania Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vascular Surgical Procedures / Aortic Aneurysm, Thoracic / Risk Assessment / Emergency Medical Services / Propensity Score / Aortic Dissection Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Eur Heart J Acute Cardiovasc Care Year: 2020 Document type: Article Affiliation country: Alemania Country of publication: Reino Unido