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Synthesis, biological evaluation, and docking studies of new pyrazole-based thiourea and sulfonamide derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase.
Ullah, Saif; El-Gamal, Mohammed I; Zaib, Sumera; Anbar, Hanan S; Zaraei, Seyed-Omar; Sbenati, Rawan M; Pelletier, Julie; Sévigny, Jean; Oh, Chang-Hyun; Iqbal, Jamshed.
Affiliation
  • Ullah S; Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan.
  • El-Gamal MI; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates; Sharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates; Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura, Mans
  • Zaib S; Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan.
  • Anbar HS; Department of Clinical Pharmacy and Pharmacotherapeutics, Dubai Pharmacy College for Girls, Dubai 19099, United Arab Emirates.
  • Zaraei SO; Sharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.
  • Sbenati RM; Sharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.
  • Pelletier J; Centre de Recherche du CHU de Québec - Université Laval, Québec, QC G1V 4G2, Canada.
  • Sévigny J; Département de microbiologie-infectiologie et d'immunologie, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada; Centre de Recherche du CHU de Québec - Université Laval, Québec, QC G1V 4G2, Canada.
  • Oh CH; Center for Biomaterials, Korea Institute of Science and Technology, PO Box 131, Cheongryang, Seoul 130-650, Republic of Korea; Department of Biomolecular Science, Korea University of Science and Technology, 113 Gwahangno, Yuseong-gu, Daejeon 305-333, Republic of Korea. Electronic address: choh@kist.
  • Iqbal J; Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan. Electronic address: drjamshed@cuiatd.edu.pk.
Bioorg Chem ; 99: 103783, 2020 06.
Article in En | MEDLINE | ID: mdl-32224334
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Sulfonamides / Thiourea / Enzyme Inhibitors / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Chem Year: 2020 Document type: Article Affiliation country: Pakistán Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Sulfonamides / Thiourea / Enzyme Inhibitors / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Chem Year: 2020 Document type: Article Affiliation country: Pakistán Country of publication: Estados Unidos