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Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing.
Bessman, Nicholas J; Mathieu, Jacques R R; Renassia, Cyril; Zhou, Lei; Fung, Thomas C; Fernandez, Keith C; Austin, Christine; Moeller, Jesper B; Zumerle, Sara; Louis, Sabine; Vaulont, Sophie; Ajami, Nadim J; Sokol, Harry; Putzel, Gregory G; Arvedson, Tara; Sockolow, Robbyn E; Lakhal-Littleton, Samira; Cloonan, Suzanne M; Arora, Manish; Peyssonnaux, Carole; Sonnenberg, Gregory F.
Affiliation
  • Bessman NJ; Jill Roberts Institute for Research in Inflammatory Bowel Disease (JRI), Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Mathieu JRR; Joan and Sanford I. Weill Department of Medicine, Division of Gastroenterology and Hepatology, Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Renassia C; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Zhou L; Université de Paris, INSERM U1016, Institut Cochin, CNRS UMR8104, 75014 Paris, France.
  • Fung TC; Laboratory of Excellence GR-Ex, Paris, France.
  • Fernandez KC; Université de Paris, INSERM U1016, Institut Cochin, CNRS UMR8104, 75014 Paris, France.
  • Austin C; Laboratory of Excellence GR-Ex, Paris, France.
  • Moeller JB; Jill Roberts Institute for Research in Inflammatory Bowel Disease (JRI), Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Zumerle S; Joan and Sanford I. Weill Department of Medicine, Division of Gastroenterology and Hepatology, Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Louis S; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Vaulont S; Jill Roberts Institute for Research in Inflammatory Bowel Disease (JRI), Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Ajami NJ; Joan and Sanford I. Weill Department of Medicine, Division of Gastroenterology and Hepatology, Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Sokol H; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Putzel GG; Jill Roberts Institute for Research in Inflammatory Bowel Disease (JRI), Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Arvedson T; Joan and Sanford I. Weill Department of Medicine, Division of Gastroenterology and Hepatology, Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Sockolow RE; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Lakhal-Littleton S; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Cloonan SM; Jill Roberts Institute for Research in Inflammatory Bowel Disease (JRI), Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Arora M; Joan and Sanford I. Weill Department of Medicine, Division of Gastroenterology and Hepatology, Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Peyssonnaux C; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA.
  • Sonnenberg GF; Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Science ; 368(6487): 186-189, 2020 04 10.
Article in En | MEDLINE | ID: mdl-32273468

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Hepcidins / Gastrointestinal Microbiome / Intestinal Diseases / Intestinal Mucosa / Iron Limits: Animals Language: En Journal: Science Year: 2020 Document type: Article Affiliation country: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Hepcidins / Gastrointestinal Microbiome / Intestinal Diseases / Intestinal Mucosa / Iron Limits: Animals Language: En Journal: Science Year: 2020 Document type: Article Affiliation country: Estados Unidos