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A Chemical Switch for Transforming a Purine Agonist for Toll-like Receptor 7 to a Clinically Relevant Antagonist.
Mukherjee, Ayan; Raychaudhuri, Deblina; Sinha, Bishnu Prasad; Kundu, Biswajit; Mitra, Mousumi; Paul, Barnali; Bandopadhyay, Purbita; Ganguly, Dipyaman; Talukdar, Arindam.
Affiliation
  • Mukherjee A; Department of Organic and Medicinal Chemistry, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Kolkata 700032, West Bengal, India.
  • Raychaudhuri D; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Sinha BP; IICB-Translational Research Unit of Excellence, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.
  • Kundu B; IICB-Translational Research Unit of Excellence, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.
  • Mitra M; Department of Organic and Medicinal Chemistry, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Kolkata 700032, West Bengal, India.
  • Paul B; IICB-Translational Research Unit of Excellence, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.
  • Bandopadhyay P; Department of Organic and Medicinal Chemistry, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Kolkata 700032, West Bengal, India.
  • Ganguly D; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Talukdar A; IICB-Translational Research Unit of Excellence, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.
J Med Chem ; 63(9): 4776-4789, 2020 05 14.
Article in En | MEDLINE | ID: mdl-32302115

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Purines / Dermatologic Agents / Toll-Like Receptor 7 Limits: Animals / Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2020 Document type: Article Affiliation country: India

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Purines / Dermatologic Agents / Toll-Like Receptor 7 Limits: Animals / Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2020 Document type: Article Affiliation country: India