Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM.

Harachi, Mio; Masui, Kenta; Honda, Hiroaki; Muragaki, Yoshihiro; Kawamata, Takakazu; Cavenee, Webster K; Mischel, Paul S; Shibata, Noriyuki

Harachi, Mio; Masui, Kenta; Honda, Hiroaki; Muragaki, Yoshihiro; Kawamata, Takakazu; Cavenee, Webster K; Mischel, Paul S; Shibata, Noriyuki.

Affiliation

Harachi M; Division of Pathological Neuroscience, Department of Pathology, Tokyo Women's Medical University, Tokyo, Japan.
Masui K; Division of Pathological Neuroscience, Department of Pathology, Tokyo Women's Medical University, Tokyo, Japan. masui-kn@twmu.ac.jp.
Honda H; Field of Human Disease Models, Major in Advanced Life Sciences and Medicine, Institute of Laboratory Animals, Tokyo Women's Medical University, Tokyo, Japan.
Muragaki Y; Department of Neurosurgery, Tokyo Women's Medical University, Japan.
Kawamata T; Department of Neurosurgery, Tokyo Women's Medical University, Japan.
Cavenee WK; Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, California.
Mischel PS; Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, California.
Shibata N; Division of Pathological Neuroscience, Department of Pathology, Tokyo Women's Medical University, Tokyo, Japan.

Mol Cancer Res ; 18(8): 1142-1152, 2020 08.

Article in En | MEDLINE | ID: mdl-32366675

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: S-Adenosylmethionine / Histones / Up-Regulation / Glioblastoma / Enhancer of Zeste Homolog 2 Protein / Mechanistic Target of Rapamycin Complex 1 / Mechanistic Target of Rapamycin Complex 2 Limits: Animals / Humans Language: En Journal: Mol Cancer Res Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2020 Document type: Article Affiliation country: Japón Country of publication: Estados Unidos

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