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The evolutionarily conserved deubiquitinase UBH1/UCH-L1 augments DAF7/TGF-ß signaling, inhibits dauer larva formation, and enhances lung tumorigenesis.
Nagata, Asami; Itoh, Fumiko; Sasho, Ayaka; Sugita, Kaho; Suzuki, Riko; Hinata, Hiroki; Shimoda, Yuta; Suzuki, Eri; Maemoto, Yuki; Inagawa, Toshihiko; Fujikawa, Yuuta; Ikeda, Eri; Fujii, Chiaki; Inoue, Hideshi.
Affiliation
  • Nagata A; Laboratory of Molecular and Chemical Biology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Itoh F; Laboratory of Cardiovascular Medicine, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan. Electronic address: mame.fumiko@gmail.com.
  • Sasho A; Laboratory of Molecular and Chemical Biology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Sugita K; Laboratory of Molecular and Chemical Biology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Suzuki R; Laboratory of Molecular and Chemical Biology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Hinata H; Laboratory of Cardiovascular Medicine, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Shimoda Y; Laboratory of Molecular and Chemical Biology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Suzuki E; Laboratory of Molecular and Chemical Biology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Maemoto Y; Laboratory of Cell Signaling, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Inagawa T; Laboratory of Cardiovascular Medicine, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Fujikawa Y; Laboratory of Molecular and Chemical Biology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Ikeda E; Laboratory of Molecular and Chemical Biology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Fujii C; Laboratory of Molecular and Chemical Biology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
  • Inoue H; Laboratory of Molecular and Chemical Biology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan. Electronic address: hinoue@toyaku.ac.jp.
J Biol Chem ; 295(27): 9105-9120, 2020 07 03.
Article in En | MEDLINE | ID: mdl-32371398
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transforming Growth Factor beta / Caenorhabditis elegans Proteins / Ubiquitin Thiolesterase / Carcinogenesis Limits: Animals Language: En Journal: J Biol Chem Year: 2020 Document type: Article Affiliation country: Japón Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transforming Growth Factor beta / Caenorhabditis elegans Proteins / Ubiquitin Thiolesterase / Carcinogenesis Limits: Animals Language: En Journal: J Biol Chem Year: 2020 Document type: Article Affiliation country: Japón Country of publication: Estados Unidos