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T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers.
Arunachalam, Prabhu S; Charles, Tysheena P; Joag, Vineet; Bollimpelli, Venkata S; Scott, Madeleine K D; Wimmers, Florian; Burton, Samantha L; Labranche, Celia C; Petitdemange, Caroline; Gangadhara, Sailaja; Styles, Tiffany M; Quarnstrom, Clare F; Walter, Korey A; Ketas, Thomas J; Legere, Traci; Jagadeesh Reddy, Pradeep Babu; Kasturi, Sudhir Pai; Tsai, Anthony; Yeung, Bertrand Z; Gupta, Shakti; Tomai, Mark; Vasilakos, John; Shaw, George M; Kang, Chil-Yong; Moore, John P; Subramaniam, Shankar; Khatri, Purvesh; Montefiori, David; Kozlowski, Pamela A; Derdeyn, Cynthia A; Hunter, Eric; Masopust, David; Amara, Rama R; Pulendran, Bali.
Affiliation
  • Arunachalam PS; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford University, Stanford, CA, USA.
  • Charles TP; Department of Pathology and Laboratory Medicine, Emory Vaccine Center, Yerkes National Primate Research Center, Atlanta, GA, USA.
  • Joag V; Department of Microbiology and Immunology, Center for Immunology, University of Minnesota, Minneapolis, MN, USA.
  • Bollimpelli VS; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA.
  • Scott MKD; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford University, Stanford, CA, USA.
  • Wimmers F; Center for Biomedical Informatics, Department of Medicine, Stanford University, Stanford, CA, USA.
  • Burton SL; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford University, Stanford, CA, USA.
  • Labranche CC; Department of Pathology and Laboratory Medicine, Emory Vaccine Center, Yerkes National Primate Research Center, Atlanta, GA, USA.
  • Petitdemange C; Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
  • Gangadhara S; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA.
  • Styles TM; HIV Inflammation and Persistence Unit, Institut Pasteur, Paris, France.
  • Quarnstrom CF; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA.
  • Walter KA; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA.
  • Ketas TJ; Department of Microbiology and Immunology, Center for Immunology, University of Minnesota, Minneapolis, MN, USA.
  • Legere T; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
  • Jagadeesh Reddy PB; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY, USA.
  • Kasturi SP; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA.
  • Tsai A; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA.
  • Yeung BZ; Pfizer, Andover, MA, USA.
  • Gupta S; Department of Pathology and Laboratory Medicine, Emory Vaccine Center, Yerkes National Primate Research Center, Atlanta, GA, USA.
  • Tomai M; Department of Microbiology and Immunology, Emory Vaccine Center, Yerkes National Primate Research Center at Emory University, Atlanta, GA, USA.
  • Vasilakos J; BioLegend, San Diego, CA, USA.
  • Shaw GM; BioLegend, San Diego, CA, USA.
  • Kang CY; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
  • Moore JP; 3M Corporate Research and Materials Lab, Saint Paul, MN, USA.
  • Subramaniam S; 3M Drug Delivery Systems, Saint Paul, MN, USA.
  • Khatri P; Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Montefiori D; Department of Microbiology and Immunology, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, Canada.
  • Kozlowski PA; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY, USA.
  • Derdeyn CA; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
  • Hunter E; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford University, Stanford, CA, USA.
  • Masopust D; Center for Biomedical Informatics, Department of Medicine, Stanford University, Stanford, CA, USA.
  • Amara RR; Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
  • Pulendran B; Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Nat Med ; 26(6): 932-940, 2020 06.
Article in En | MEDLINE | ID: mdl-32393800
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Products, gag / Simian Acquired Immunodeficiency Syndrome / Simian Immunodeficiency Virus / SAIDS Vaccines / CD8-Positive T-Lymphocytes / Antibodies, Neutralizing / Immunity, Cellular / Antibodies, Viral Limits: Animals Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Products, gag / Simian Acquired Immunodeficiency Syndrome / Simian Immunodeficiency Virus / SAIDS Vaccines / CD8-Positive T-Lymphocytes / Antibodies, Neutralizing / Immunity, Cellular / Antibodies, Viral Limits: Animals Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos