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Epigenome-wide association study and multi-tissue replication of individuals with alcohol use disorder: evidence for abnormal glucocorticoid signaling pathway gene regulation.
Lohoff, Falk W; Roy, Arunima; Jung, Jeesun; Longley, Martha; Rosoff, Daniel B; Luo, Audrey; O'Connell, Emma; Sorcher, Jill L; Sun, Hui; Schwandt, Melanie; Hodgkinson, Colin A; Goldman, David; Momenan, Reza; McIntosh, Andrew M; Adams, Mark J; Walker, Rosie M; Evans, Kathryn L; Porteous, David; Smith, Alicia K; Lee, Jisoo; Muench, Christine; Charlet, Katrin; Clarke, Toni-Kim; Kaminsky, Zachary A.
Affiliation
  • Lohoff FW; Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA. falk.lohoff@nih.gov.
  • Roy A; Royal's Institute of Mental Health Research, University of Ottawa, Ottawa, Canada.
  • Jung J; Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
  • Longley M; Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
  • Rosoff DB; Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
  • Luo A; Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
  • O'Connell E; Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
  • Sorcher JL; Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
  • Sun H; Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
  • Schwandt M; Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
  • Hodgkinson CA; Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
  • Goldman D; Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
  • Momenan R; Clinical Neuroimaging Research Core, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
  • McIntosh AM; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
  • Adams MJ; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
  • Walker RM; Medical Genetic Section, Centre for Genomic and Experimental Medicine, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
  • Evans KL; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
  • Porteous D; Medical Genetic Section, Centre for Genomic and Experimental Medicine, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
  • Smith AK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
  • Lee J; Medical Genetic Section, Centre for Genomic and Experimental Medicine, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
  • Muench C; Department of Gynecology and Obstetrics, Emory University, Atlanta, Georgia, USA.
  • Charlet K; Department of Psychiatry & Behavioral Sciences, Emory University, Atlanta, GA, USA.
  • Clarke TK; Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
  • Kaminsky ZA; Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Mol Psychiatry ; 26(6): 2224-2237, 2021 06.
Article in En | MEDLINE | ID: mdl-32398718
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alcoholism / Glucocorticoids Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Mol Psychiatry Journal subject: BIOLOGIA MOLECULAR / PSIQUIATRIA Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alcoholism / Glucocorticoids Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Mol Psychiatry Journal subject: BIOLOGIA MOLECULAR / PSIQUIATRIA Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido