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Quantitative single-molecule imaging of TNFR1 reveals zafirlukast as antagonist of TNFR1 clustering and TNFα-induced NF-ĸB signaling.
Weinelt, Nadine; Karathanasis, Christos; Smith, Sonja; Medler, Juliane; Malkusch, Sebastian; Fulda, Simone; Wajant, Harald; Heilemann, Mike; van Wijk, Sjoerd J L.
Affiliation
  • Weinelt N; Institute for Experimental Cancer Research in Pediatrics, Goethe University, Frankfurt am Main, Germany.
  • Karathanasis C; Institute of Physical and Theoretical Chemistry, Goethe University, Frankfurt am Main, Germany.
  • Smith S; Institute for Experimental Cancer Research in Pediatrics, Goethe University, Frankfurt am Main, Germany.
  • Medler J; Division of Molecular Internal Medicine, Department of Internal Medicine II, University Hospital Würzburg, Auverahaus, Würzburg, Germany.
  • Malkusch S; Institute of Clinical Pharmacology, Goethe-University, Frankfurt am Main, Germany.
  • Fulda S; Institute for Experimental Cancer Research in Pediatrics, Goethe University, Frankfurt am Main, Germany.
  • Wajant H; German Cancer Consortium (DKTK), Partner site Frankfurt am Main, Germany.
  • Heilemann M; German Cancer Research Centre (DKFZ), Heidelberg, Germany.
  • van Wijk SJL; Division of Molecular Internal Medicine, Department of Internal Medicine II, University Hospital Würzburg, Auverahaus, Würzburg, Germany.
J Leukoc Biol ; 109(2): 363-371, 2021 02.
Article in En | MEDLINE | ID: mdl-32401398
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tosyl Compounds / Signal Transduction / NF-kappa B / Tumor Necrosis Factor-alpha / Receptors, Tumor Necrosis Factor, Type I / Single Molecule Imaging Limits: Animals / Humans Language: En Journal: J Leukoc Biol Year: 2021 Document type: Article Affiliation country: Alemania Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tosyl Compounds / Signal Transduction / NF-kappa B / Tumor Necrosis Factor-alpha / Receptors, Tumor Necrosis Factor, Type I / Single Molecule Imaging Limits: Animals / Humans Language: En Journal: J Leukoc Biol Year: 2021 Document type: Article Affiliation country: Alemania Country of publication: Reino Unido