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Novel bacterial topoisomerase inhibitors derived from isomannide.
Okumu, Antony; Lu, Yanran; Dellos-Nolan, Sheri; Papa, Jonathan L; Koci, Bryan; Cockroft, Nicholas T; Gallucci, Judith; Wozniak, Daniel J; Yalowich, Jack C; Mitton-Fry, Mark J.
Affiliation
  • Okumu A; Division of Medicinal Chemistry and Pharmacognosy. The Ohio State University, Columbus, OH, 43210, USA.
  • Lu Y; Division of Medicinal Chemistry and Pharmacognosy. The Ohio State University, Columbus, OH, 43210, USA.
  • Dellos-Nolan S; Microbial Infection and Immunity. The Ohio State University, Columbus, OH, 43210, USA.
  • Papa JL; Division of Pharmaceutics and Pharmacology. The Ohio State University, Columbus, OH, 43210, USA.
  • Koci B; Eurofins Panlabs. St. Charles, MO, 63304, USA.
  • Cockroft NT; Division of Medicinal Chemistry and Pharmacognosy. The Ohio State University, Columbus, OH, 43210, USA.
  • Gallucci J; Department of Chemistry and Biochemistry. The Ohio State University, Columbus, OH, 43210, USA.
  • Wozniak DJ; Microbial Infection and Immunity. The Ohio State University, Columbus, OH, 43210, USA; Department of Microbiology. The Ohio State University, Columbus, OH, 43210, USA.
  • Yalowich JC; Division of Pharmaceutics and Pharmacology. The Ohio State University, Columbus, OH, 43210, USA.
  • Mitton-Fry MJ; Division of Medicinal Chemistry and Pharmacognosy. The Ohio State University, Columbus, OH, 43210, USA. Electronic address: mitton-fry.1@osu.edu.
Eur J Med Chem ; 199: 112324, 2020 Aug 01.
Article in En | MEDLINE | ID: mdl-32402932
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bridged Bicyclo Compounds, Heterocyclic / Topoisomerase Inhibitors / Gram-Positive Bacteria / Anti-Bacterial Agents Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Francia
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bridged Bicyclo Compounds, Heterocyclic / Topoisomerase Inhibitors / Gram-Positive Bacteria / Anti-Bacterial Agents Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Francia