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Encapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity.
Shkodra-Pula, Blerina; Kretzer, Christian; Jordan, Paul M; Klemm, Paul; Koeberle, Andreas; Pretzel, David; Banoglu, Erden; Lorkowski, Stefan; Wallert, Maria; Höppener, Stephanie; Stumpf, Steffi; Vollrath, Antje; Schubert, Stephanie; Werz, Oliver; Schubert, Ulrich S.
Affiliation
  • Shkodra-Pula B; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.
  • Kretzer C; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Philosophenweg 14, 07743, Jena, Germany.
  • Jordan PM; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Philosophenweg 14, 07743, Jena, Germany.
  • Klemm P; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.
  • Koeberle A; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Philosophenweg 14, 07743, Jena, Germany.
  • Pretzel D; Michael Popp Reseach Institute, University of Innsbruck, Mitterweg 24, 6020, Innsbruck, Austria.
  • Banoglu E; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.
  • Lorkowski S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Gazi University, Etiler, Yenimahalle, 06330, Ankara, Turkey.
  • Wallert M; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
  • Höppener S; Institute of Nutritional Sciences, Friedrich Schiller University Jena, Dornburger Straße 25, 07743, Jena, Germany.
  • Stumpf S; Institute of Nutritional Sciences, Friedrich Schiller University Jena, Dornburger Straße 25, 07743, Jena, Germany.
  • Vollrath A; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.
  • Schubert S; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743, Jena, Germany.
  • Werz O; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.
  • Schubert US; Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstraße 10, 07743, Jena, Germany.
J Nanobiotechnology ; 18(1): 73, 2020 May 14.
Article in En | MEDLINE | ID: mdl-32408877
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Dextrans / Nanoparticles / Polylactic Acid-Polyglycolic Acid Copolymer / Isoxazoles Limits: Adult / Humans Language: En Journal: J Nanobiotechnology Year: 2020 Document type: Article Affiliation country: Alemania Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Dextrans / Nanoparticles / Polylactic Acid-Polyglycolic Acid Copolymer / Isoxazoles Limits: Adult / Humans Language: En Journal: J Nanobiotechnology Year: 2020 Document type: Article Affiliation country: Alemania Country of publication: Reino Unido