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Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors.
Rothe, Katharina; Babaian, Artem; Nakamichi, Naoto; Chen, Min; Chafe, Shawn C; Watanabe, Akie; Forrest, Donna L; Mager, Dixie L; Eaves, Connie J; Dedhar, Shoukat; Jiang, Xiaoyan.
Affiliation
  • Rothe K; Terry Fox Laboratory, BC Cancer, Vancouver, BC V5Z 1L3, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. Electronic address: krothe@bccrc.ca.
  • Babaian A; Terry Fox Laboratory, BC Cancer, Vancouver, BC V5Z 1L3, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Nakamichi N; Terry Fox Laboratory, BC Cancer, Vancouver, BC V5Z 1L3, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Chen M; Terry Fox Laboratory, BC Cancer, Vancouver, BC V5Z 1L3, Canada.
  • Chafe SC; Genetics Unit, Integrative Oncology, BC Cancer, Vancouver, BC V5Z 1L3, Canada.
  • Watanabe A; Terry Fox Laboratory, BC Cancer, Vancouver, BC V5Z 1L3, Canada.
  • Forrest DL; Department of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada; Leukemia/Bone Marrow Transplant Program of British Columbia, Vancouver, BC V5Z 1M9, Canada.
  • Mager DL; Terry Fox Laboratory, BC Cancer, Vancouver, BC V5Z 1L3, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Eaves CJ; Terry Fox Laboratory, BC Cancer, Vancouver, BC V5Z 1L3, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada; Department of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Dedhar S; Genetics Unit, Integrative Oncology, BC Cancer, Vancouver, BC V5Z 1L3, Canada; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Jiang X; Terry Fox Laboratory, BC Cancer, Vancouver, BC V5Z 1L3, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada; Department of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. Electronic address: xjiang@bccrc.ca.
Cell Stem Cell ; 27(1): 110-124.e9, 2020 07 02.
Article in En | MEDLINE | ID: mdl-32413332
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Fusion Proteins, bcr-abl Limits: Humans Language: En Journal: Cell Stem Cell Year: 2020 Document type: Article Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Fusion Proteins, bcr-abl Limits: Humans Language: En Journal: Cell Stem Cell Year: 2020 Document type: Article Country of publication: Estados Unidos