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HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease.
Pao, Ping-Chieh; Patnaik, Debasis; Watson, L Ashley; Gao, Fan; Pan, Ling; Wang, Jun; Adaikkan, Chinnakkaruppan; Penney, Jay; Cam, Hugh P; Huang, Wen-Chin; Pantano, Lorena; Lee, Audrey; Nott, Alexi; Phan, Trongha X; Gjoneska, Elizabeta; Elmsaouri, Sara; Haggarty, Stephen J; Tsai, Li-Huei.
Affiliation
  • Pao PC; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Patnaik D; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Watson LA; Chemical Neurobiology Laboratory, Departments of Neurology and Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.
  • Gao F; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Pan L; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Wang J; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Adaikkan C; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Penney J; Caltech Bioinformatics Resource Center at Beckman Institute of Caltech, Pasadena, CA, 91225, USA.
  • Cam HP; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Huang WC; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Pantano L; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Lee A; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Nott A; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Phan TX; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Gjoneska E; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Elmsaouri S; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Haggarty SJ; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Tsai LH; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Nat Commun ; 11(1): 2484, 2020 05 18.
Article in En | MEDLINE | ID: mdl-32424276
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Brain / Aging / Oxidative Stress / DNA Glycosylases / Histone Deacetylase 1 / Alzheimer Disease Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Brain / Aging / Oxidative Stress / DNA Glycosylases / Histone Deacetylase 1 / Alzheimer Disease Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido