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Catalytically inactive T7 DNA polymerase imposes a lethal replication roadblock.
Hernandez, Alfredo J; Lee, Seung-Joo; Chang, Seungwoo; Lee, Jaehun A; Loparo, Joseph J; Richardson, Charles C.
Affiliation
  • Hernandez AJ; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.
  • Lee SJ; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.
  • Chang S; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.
  • Lee JA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.
  • Loparo JJ; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.
  • Richardson CC; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA ccr@hms.harvard.edu.
J Biol Chem ; 295(28): 9542-9550, 2020 07 10.
Article in En | MEDLINE | ID: mdl-32430399

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thioredoxins / DNA, Viral / Bacteriophage T7 / Escherichia coli Proteins / DNA-Directed DNA Polymerase / DNA Replication / Escherichia coli Language: En Journal: J Biol Chem Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thioredoxins / DNA, Viral / Bacteriophage T7 / Escherichia coli Proteins / DNA-Directed DNA Polymerase / DNA Replication / Escherichia coli Language: En Journal: J Biol Chem Year: 2020 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos