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A Novel Physiologically Based Model of Creatinine Renal Disposition to Integrate Current Knowledge of Systems Parameters and Clinical Observations.
Scotcher, Daniel; Arya, Vikram; Yang, Xinning; Zhao, Ping; Zhang, Lei; Huang, Shiew-Mei; Rostami-Hodjegan, Amin; Galetin, Aleksandra.
Affiliation
  • Scotcher D; Centre for Applied Pharmacokinetic Research, University of Manchester, Manchester, UK.
  • Arya V; Office of Clinical Pharmacology, Office of Translational Sciences, Centre for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Yang X; Office of Clinical Pharmacology, Office of Translational Sciences, Centre for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Zhao P; Office of Clinical Pharmacology, Office of Translational Sciences, Centre for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Zhang L; Office of Research and Standards, Office of Generic Drugs, Centre for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Huang SM; Office of Clinical Pharmacology, Office of Translational Sciences, Centre for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.
  • Rostami-Hodjegan A; Centre for Applied Pharmacokinetic Research, University of Manchester, Manchester, UK.
  • Galetin A; Certara, Sheffield, UK.
CPT Pharmacometrics Syst Pharmacol ; 9(6): 310-321, 2020 06.
Article in En | MEDLINE | ID: mdl-32441889
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Creatinine / Renal Elimination / Organic Cation Transporter 2 / Kidney Tubules, Proximal / Models, Biological Type of study: Guideline Limits: Humans Language: En Journal: CPT Pharmacometrics Syst Pharmacol Year: 2020 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Creatinine / Renal Elimination / Organic Cation Transporter 2 / Kidney Tubules, Proximal / Models, Biological Type of study: Guideline Limits: Humans Language: En Journal: CPT Pharmacometrics Syst Pharmacol Year: 2020 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos